Results 261 to 270 of about 2,516,689 (307)

Structure and Function of DNA Methyltransferases

Annual Review of Biophysics and Biomolecular Structure, 1995
In prokaryotes, the major role of DNA methylation is to protect host DNA against degradation by restriction enzymes. In eukaryotes, DNA methylation has been implicated in the control of several cellular processes, including differentiation, gene regulation, and embryonic development.
openaire   +2 more sources

DNA Methyltransferase Probing of DNA-Protein Interactions

2006
Effective methods of probing chromatin structure without disrupting DNA-protein interactions and associations are necessary for creating an accurate picture of chromatin and its processes in vivo. Expression of cytidine-5 DNA methyltransferases (C5 DMTases) in Saccharomyces cerevisiae provides a powerful noninvasive method of assaying relative DNA ...
Scott A, Hoose, Michael P, Kladde
openaire   +2 more sources

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.

Cell, 1992
E. Li, T. Bestor, R. Jaenisch
semanticscholar   +1 more source

DNA Methylation and DNA Methyltransferase in Wheat

1988
Plant DNA is distinguished from the deoxyribonucleic acid of all other eukaryotic organisms by its substantial amount of the modified base, 5-methylcytosine (mCyt). mCyt is not detectable in most fungi and in invertebrates, it constitutes only up to 1% of the bases in vertebrate DNA, but it contributes 5–8 mol% of the total base composition in average ...
Hartmut Follmann, Roland Schleicher, Jörg Balzer   +2 more
openaire   +1 more source

The DNA methyltransferase family: a versatile toolkit for epigenetic regulation

Nature reviews genetics, 2017
F. Lyko
semanticscholar   +1 more source

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

Nature, 2004
M. Kaneda, Masaki Okano, K. Hata, T. Sado, N. Tsujimoto, E. Li, H. Sasaki   +6 more
semanticscholar   +1 more source

Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2

Science, 2006
M. Goll, F. Kirpekar, K. Maggert, J. Yoder, C. Hsieh, Xiaoyu Zhang, K. Golic, S. Jacobsen, T. Bestor   +8 more
semanticscholar   +1 more source

The DNA methyltransferase DNMT3C protects male germ cells from transposon activity

Science, 2016
Joan Barau, Aurélie Teissandier, N. Zamudio, Stéphanie Roy, Valérie Nalesso, Y. Hérault, F. Guillou, D. Bourc’his   +7 more
semanticscholar   +1 more source

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

Nature Genetics, 2000
F. Fuks, W. Burgers, A. Brehm, L. Hughes-Davies, T. Kouzarides   +4 more
semanticscholar   +1 more source

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

Nature Genetics, 2011
Xiao-jing Yan, Jie Xu, Zhao-hui Gu, Chun-ming Pan, G. Lu, Yang Shen, Jing-yi Shi, Yong-mei Zhu, L. Tang, Xiao-Wei Zhang, Wenxue Liang, J. Mi, Huai-Dong Song, Ke-Qin Li, Zhu Chen, Saijuan Chen   +15 more
semanticscholar   +1 more source