Results 171 to 180 of about 141,545 (201)
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The Application of Delivery Systems for DNA Methyltransferase Inhibitors

BioDrugs, 2011
DNA methylation, which often occurs at the cytosine residue of cytosine-guanine dinucleotides, is critical for the control of gene expression and mitotic inheritance in eukaryotes. DNA methylation silences gene expression either by directly hindering the access of transcription factors to the target DNA, or through recruitment of histone deacetylases ...
Lim, S.   +4 more
openaire   +3 more sources

Structure-Guided Optimization of DNA Methyltransferase Inhibitors

2016
no ...
Erdmann, Alexandre   +2 more
openaire   +1 more source

Combination therapy with DNA methyltransferase inhibitors in hematologic malignancies

Nature Clinical Practice Oncology, 2005
A variety of epigenetic changes contribute to transcriptional dysregulation in myelodysplastic syndromes (MDSs) and acute myeloid leukemia (AML). DNA methyltransferase (DNMT) inhibitors--azacitidine and decitabine--have significant activity in the treatment of MDS.
openaire   +2 more sources

Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions

Ca-A Cancer Journal for Clinicians, 2021
Michael L Cheng   +2 more
exaly  

DNA Methyltransferase Inhibitors

2010
Nicola Simola   +141 more
openaire   +1 more source

DNA Methyltransferase Inhibitors

2016
Noël J.-M. Raynal, Jean-Pierre J. Issa
openaire   +1 more source

DNA methyltransferase inhibitors: Class effect or unique agents?

Leukemia & Lymphoma, 2008
Elizabeth A, Griffiths, Steven D, Gore
openaire   +2 more sources

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