Results 91 to 100 of about 2,560,073 (378)

Multicolor Fluorescent Differential Display

BioTechniques, 2001
Differential display and DNA microarray have emerged as the two most popular methods for gene expression profiling. Here, we developed a multicolor fluorescent differential display (FDD) method that combines the virtues of both differential display in ...
Y.-j. Cho, J.D. Meade, J.C. Walden, X. Chen, Z. Guo, P. Liang   +5 more
doaj   +1 more source

Systems Biology and the Development of Vaccines and Drugs for Malaria Treatments [PDF]

, 2006
The sequencing race has ended and the functional race has already begun. Microarray technology enables simultaneous gene expression analysis of thousands of genes, enabling a snapshot of an organisms’ transcriptome at an unprecedented resolution.
Adebiyi, E. F.
core   +1 more source

Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum [PDF]

, 2008
As nonreplicating tubercle bacilli are tolerant to the cidal action of antibiotics and resistant to multiple stresses, identification of this persister-like population of tubercle bacilli in sputum presents exciting and tractable new opportunities to ...
Alvarez, Anna L Sherratt, Bacon, Beste, Betts, Canetti, Claire Senner, Cole, Connolly, Conway, Daniel, Daugelat, Desjardin, Dhar, Dubnau, Eisen, Fenhalls, Fleischmann, Garnier, Garton, Gomez, Gurdyal S Besra, Jason Hinds, Kalscheuer, Karakousis, Kendall, Kolter, Kumar, Kumar Rajakumar, Larsen, Levin, Mangan, Manganelli, McKinney, Michael R Barer, Mitchison, Mitchison, Monahan, Mukamolova, Munoz-Elias, Murphy, Muttucumaru, Nakagawa, Natalie J Garton, Neyrolles, Olivier Neyrolles, Paramasivan, Park, Philip D Butcher, Rachman, Rajakumar, Rebecca J Smith, Reed, Richard A Adegbola, Rohde, Schnappinger, Shi, Siegele, Simon J Waddell, Sirakova, Smeulders, Sommers, Stewart, Su-Min Lee, Talaat, Talaat, Timm, Van der Geize, Voskuil, Waddell, Waddell, Waddell, Waltermann, Wayne, Wayne, Weichart, Wilkinson, Young   +77 more
core   +4 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Microarray Applications in Neuroscience

Neurobiology of Disease, 2001
Advances in all facets of technology from molecular biology to imaging and computational biology offer unprecedented opportunities for improving our understanding of the brain in health and disease.
Zheng Luo, Daniel H. Geschwind
doaj   +1 more source

Real-time DNA microarray analysis [PDF]

, 2009
We present a quantification method for affinity-based DNA microarrays which is based on the real-time measurements of hybridization kinetics. This method, i.e.
Abdueva, Arjang Hassibi, Babak Hassibi, Bassil, Beissbarth, Belosludtsev, Berg, Bishop, Chee, Chen, Dai, Das, Fritz, Georgiadis, Ghosh, Hall, Hardenbol, Haris Vikalo, Hassibi, Hassibi, Hassibi, Heaton, Homola, Hubble, Huber, José Luis Riechmann, Kennedy, Lacowicz, Levine, Linneti, Lockhart, Lockhart, Marras, Okamura, Ota, Pease, Peterson, Rajendran, SantaLucia, Savran, Schena, Schena, Schienle, Shalon, Skvortsov, Smith, Steinfield, Stimpson, Su, Towery, Tu, Van Kampen, Vikalo, Wang, Watterson, Yamaguchi, Zeng   +56 more
core   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

A Platform for Combined DNA and Protein Microarrays Based on Total Internal Reflection Fluorescence

Sensors, 2012
We have developed a novel microarray technology based on total internal reflection fluorescence (TIRF) in combination with DNA and protein bioassays immobilized at the TIRF surface.
Alexander Asanov, Angélica Zepeda, Luis Vaca   +2 more
doaj   +1 more source

Magnetic Scanometric DNA Microarray Detection of Methyl Tertiary Butyl Ether Degrading Bacteria for Environmental Monitoring [PDF]

, 2011
A magnetoresistive biosensing platform based on a single magnetic tunnel junction (MTJ) scanning probe and DNA microarrays labeled with magnetic particles has been developed to provide an inexpensive, sensitive and reliable detection of DNA.
Chan, Mei-Lin, Horsley, David A., Hristova, Krassimira R., Jaramillo, Gerardo   +3 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source