Results 81 to 90 of about 1,802,261 (296)

GeneRank: Using search engine technology for the analysis of microarray experiments [PDF]

, 2005
Copyright @ 2005 Morrison et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use ...
Morrison Julie L, Desmond J Higham, Morrison, J.L., Breitling, Rainer, Gilbert, D, Breitling, R., Rainer Breitling, Gilbert, David R., Breitling, R, Gilbert, David R, Breitling Rainer, Higham, Desmond J, Higham, Desmond J., Morrison, Julie L., Gilbert, D.R., Julie L Morrison, Higham Desmond J, Morrison, Julie L, David R Gilbert, Morrison, JL, Gilbert David R, Higham, D.J., Higham, D   +22 more
core   +2 more sources

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

Array-based Identification of Copy Number Changes in a Diagnostic Setting : Simultaneous gene-focused and low resolution whole human genome analysis

Sultan Qaboos University Medical Journal, 2013
Objectives: The aim of this study was to develop and validate a comparative genomic hybridisation (CGH) array that would allow simultaneous targeted analysis of a panel of disease genes and low resolution whole genome analysis.
Renate Marquis-Nicholson, Elaine Doherty, Jennifer M. Love, Chuan-Ching Lan, Alice M. George, Anthony Thrush, Donald R. Love   +6 more
doaj  

Array-A-Lizer: A serial DNA microarray quality analyzer

BMC Bioinformatics, 2004
Background The proliferate nature of DNA microarray results have made it necessary to implement a uniform and quick quality control of experimental results to ensure the consistency of data across multiple experiments prior to actual data analysis ...
Matthiessen Mads, Fleckner Jan, Petri Andreas   +2 more
doaj   +1 more source

Microarray analysis of defined Mycobacterium tuberculosis populations using RNA amplification strategies. [PDF]

, 2008
BACKGROUND: The amplification of bacterial RNA is required if complex host-pathogen interactions are to be studied where the recovery of bacterial RNA is limited.
Laing Ken, Waddell, SJ, Butcher, PD, Senner Claire, Simon Waddell (4462816), Ken Laing, Laing, K, Ken Laing (173955), Philip D Butcher, Waddell Simon J, Butcher Philip D, Claire Senner (44405), Simon J Waddell, Claire Senner, Senner, C, Philip D Butcher (16047203)   +15 more
core   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

Multicolor Fluorescent Differential Display

BioTechniques, 2001
Differential display and DNA microarray have emerged as the two most popular methods for gene expression profiling. Here, we developed a multicolor fluorescent differential display (FDD) method that combines the virtues of both differential display in ...
Y.-j. Cho, J.D. Meade, J.C. Walden, X. Chen, Z. Guo, P. Liang   +5 more
doaj   +1 more source

Hot Transcriptomics [PDF]

, 2010
DNA microarray technology allows for a quick and easy comparison of complete transcriptomes, resulting in improved molecular insight in fluctuations of gene expression.
van der Oost, J., Jasper Walther, Oost, J., van der, Walther, J., Pawel Sierocinski, Sierocinski, P., John van der Oost   +6 more
core   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Microarray Applications in Neuroscience

Neurobiology of Disease, 2001
Advances in all facets of technology from molecular biology to imaging and computational biology offer unprecedented opportunities for improving our understanding of the brain in health and disease.
Zheng Luo, Daniel H. Geschwind
doaj   +1 more source