Results 51 to 60 of about 410,424 (355)

A Novel Bio-Inspired Hybrid Multi-Filter Wrapper Gene Selection Method with Ensemble Classifier for Microarray Data [PDF]

arXiv, 2021
Microarray technology is known as one of the most important tools for collecting DNA expression data. This technology allows researchers to investigate and examine types of diseases and their origins. However, microarray data are often associated with challenges such as small sample size, a significant number of genes, imbalanced data, etc.
arxiv  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray

BMC Genomics, 2007
Background Mycotoxins are fungal secondary metabolites commonly present in feed and food, and are widely regarded as hazardous contaminants. Citrinin, one of the very well known mycotoxins that was first isolated from Penicillium citrinum, is produced by
Nobumasa Hitoshi, Ishizawa Yo-hei, Ueda Youji, Suzuki Yoshiteru, Kitagawa Emiko, Iwahashi Hitoshi, Kuboki Yoshihide, Hosoda Hiroshi, Iwahashi Yumiko   +8 more
doaj   +1 more source

Genomic alterations in primary gastric adenocarcinomas correlate with clinicopathological characteristics and survival. [PDF]

, 2004
Background & aimsPathogenesis of gastric cancer is driven by an accumulation of genetic changes that to a large extent occur at the chromosomal level. In order to investigate the patterns of chromosomal aberrations in gastric carcinomas, we performed
Albertson, Donna, Kuipers, Ernst J, Meijer, Gerrit A, Meuwissen, Stefan GM, Pinkel, Daniel, Postma, Cindy, Snijders, Antoine M, Weiss, Marjan M   +7 more
core   +3 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53 [PDF]

, 2010
Background: The availability of various "omics" datasets creates a prospect of performing the study of genome-wide genetic regulatory networks. However, one of the major challenges of using mathematical models to infer genetic regulation from microarray ...
A Chipperfield, A Conesa, AR Joyce, AT Kwon, AW Braithwaite, C Moorman, CG Moles, CL Wei, D Chen, DG Sedding, E Wingender, G Liu, H de Jong, J Aach, J Goutsias, J Goutsias, J Wang, J Wang, J Wang, J Wang, JC Liao, JM Espinosa, Junbai Wang, K Zhu, KB Spurgers, KH Vousden, L Ma, M Barenco, MK Yeung, MR Bhonde, MV Karamouzis, N Sun, PS Kho, Q Wei, Q Wu, R Rahman-Roblick, RB Zhao, RC Gentleman, RS Erb, S Liu, S Rogers, SA Johnson, T Tian, Tianhai Tian, TS Gardner, TT Vu, WS el Deiry   +46 more
core   +4 more sources

Estimating the proportion of differentially expressed genes in comparative DNA microarray experiments [PDF]

IMS Lecture Notes Monograph Series 2007, Vol. 54, 92-102, 2007
DNA microarray experiments, a well-established experimental technique, aim at understanding the function of genes in some biological processes. One of the most common experiments in functional genomics research is to compare two groups of microarray data to determine which genes are differentially expressed.
arxiv   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Digital microarrays: single-molecule readout with interferometric detection of plasmonic nanorod labels [PDF]

, 2018
DNA and protein microarrays are a high-throughput technology that allow the simultaneous quantification of tens of thousands of different biomolecular species.
Daaboul, George G., Kanik, Fulya Ekiz, Sevenler, Derin, Unlu, M. Selim, Unlu, Nese Lortlar   +4 more
core   +1 more source

DNA-microarrays and food-biotechnology [PDF]

, 1999
The recent boost in bacterial genome sequences (e.g. Kunst et al. 1997; Bolotin et al. 1999) now enables true ‘functional genomics’ studies, including transcriptome- proteome- and metabolome analyses as well as structural genomics. For these areas novel high-throughput analytical methods have been developed, such as DNA-microarrays and improved 2D ...
Jan Kok, Leendert W. Hamoen, Siger Holsappel, Sierd Bron, Oscar P. Kuipers, Anne de Jong   +5 more
openaire   +5 more sources