Results 51 to 60 of about 2,560,073 (378)

Integrative Model-based clustering of microarray methylation and expression data [PDF]

, 2012
In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics.
Booth, James G., Figueroa, Maria E., Kormaksson, Matthias, Melnick, Ari   +3 more
core   +1 more source

On Limits of Performance of Dna Microarrays [PDF]

2006 IEEE International Conference on Acoustics Speed and Signal Processing Proceedings, 2006
DNA microarray technology relies on the hybridization process which is stochastic in nature. Probabilistic cross-hybridization of non-specific targets, as well as the shot-noise originating from specific targets binding, are among the many obstacles for achieving high accuracy in DNA microarray analysis.
Vikalo, H., Hassibi, B., Hassibi, A.
openaire   +4 more sources

Automated evaluation and normalization of immunohistochemistry on tissue microarrays with a DNA microarray scanner

BioTechniques, 2003
Hundreds of tissue samples may be assembled in a tissue microarray format for simultaneous immunostaining assessment of protein expression profiling. A DNA microarray two-color laser scanner was used for automated analysis of tissue microarray indirect ...
Wolfgang Haedicke, Helmut H. Popper, Charles R. Buck, Kurt Zatloukal   +3 more
doaj   +1 more source

Nucleic acid - protein fingerprints. Novel protein classification based on nucleic acid - protein recognition [PDF]

, 2012
Protein chemistry uses protein description and classification based on molecular mass and isoelectric point as general features. Enzymes are also compared by enzymatic reaction constants, namely Km and kcat values. Proteins are also studied by binding to
Alexander Krylov, Renad Zhdanov
core   +1 more source

Genomic alterations in primary gastric adenocarcinomas correlate with clinicopathological characteristics and survival. [PDF]

, 2004
Background & aimsPathogenesis of gastric cancer is driven by an accumulation of genetic changes that to a large extent occur at the chromosomal level. In order to investigate the patterns of chromosomal aberrations in gastric carcinomas, we performed
Albertson, Donna, Kuipers, Ernst J, Meijer, Gerrit A, Meuwissen, Stefan GM, Pinkel, Daniel, Postma, Cindy, Snijders, Antoine M, Weiss, Marjan M   +7 more
core   +3 more sources

Comparison of dkgB-linked intergenic sequence ribotyping to DNA microarray hybridization for assigning serotype to Salmonella enterica

FEMS Microbiology Letters, 2012
Two DNA-based methods were compared for the ability to assign serotype to 139 isolates of Salmonella enterica ssp. I. Intergenic sequence ribotyping (ISR) evaluated single nucleotide polymorphisms occurring in a 5S ribosomal gene region and flanking ...
J. Guard, Roxana Sánchez-Ingunza, C. Morales, Tod Stewart, K. Liljebjelke, J. Kessel, K. Ingram, Deana R. Jones, C. Jackson, P. Fedorka-Cray, J. Frye, R. Gast, A. Hinton   +12 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Detection of Multiple Human Papillomavirus Genotypes in Anal Carcinoma

Infectious Agents and Cancer, 2010
Infection with human papillomavirus (HPV) is a major risk factor for development of anal squamous cell carcinoma. Despite over 100 genotypes of the virus, HPV 16 and 18 are considered pathogenic as they are seen in the majority of cervical and anal ...
Luo Linda, Liu Yu-Tsueng, Ramamoorthy Sonia, Miyai Katsumi, Lu Qing, Carethers John M   +5 more
doaj   +1 more source

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]

, 2006
A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G, Chiu, Charles Y, DeRisi, Joseph L, Eckburg, Paul B, Fischer, Kael, Ganem, Don, Koshy, Anita, Merker, Jason D, Patterson, Bruce K, Rouskin, Silvi, Schnurr, David, Tompkins, Lucy S, Urisman, Anatoly, Yagi, Shigeo   +13 more
core  

Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53 [PDF]

, 2010
Background: The availability of various "omics" datasets creates a prospect of performing the study of genome-wide genetic regulatory networks. However, one of the major challenges of using mathematical models to infer genetic regulation from microarray ...
A Chipperfield, A Conesa, AR Joyce, AT Kwon, AW Braithwaite, C Moorman, CG Moles, CL Wei, D Chen, DG Sedding, E Wingender, G Liu, H de Jong, J Aach, J Goutsias, J Goutsias, J Wang, J Wang, J Wang, J Wang, JC Liao, JM Espinosa, Junbai Wang, K Zhu, KB Spurgers, KH Vousden, L Ma, M Barenco, MK Yeung, MR Bhonde, MV Karamouzis, N Sun, PS Kho, Q Wei, Q Wu, R Rahman-Roblick, RB Zhao, RC Gentleman, RS Erb, S Liu, S Rogers, SA Johnson, T Tian, Tianhai Tian, TS Gardner, TT Vu, WS el Deiry   +46 more
core   +4 more sources