Results 281 to 290 of about 297,565 (330)

Evolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein

, 2017
Bharat Lakhani, Kelly M. Thayer, Manju Hingorani, David L. Beveridge   +3 more
openalex   +1 more source

The interplay between tissue‐resident microbiome and host proteins by integrated multi‐omics during progression of colorectal adenoma to carcinoma

iMeta, EarlyView.
This study integrated metagenomic and proteomic profiling of 185 colorectal tissue samples—spanning adenoma (A), tumor (T), and para‐tumor (P)—to characterize multi‐kingdom microbiome and host protein dynamics in colorectal cancer (CRC). In total, 4057 bacterial, 61 fungal, 108 archaeal, and 374 viral species were identified, revealing CRC‐specific ...
Di Wu, An‐Jun Wang, De‐Chao Bu, Yan‐Yan Sun, Chen‐Hao Li, Yue‐Mei Hong, Shan Zhang, Shi‐Yang Chen, Jin‐An Zhou, Tian‐Yi Zhang, Min‐Hao Yu, Yong‐Jing Ma, Xiu‐Li Wang, Jia Xu, Wei He, Christopher Heeschen, Jian‐Feng Chen, Wen‐Jun Mao, Hui Ding, Wen‐Juan Wu, Yi Zhao, Hui Wang, Ning‐Ning Liu   +22 more
wiley   +1 more source

Dissecting DNA-mismatch-repair-driven mutational processes in human cells

Owusu M, Menche J, Loizou J, Weghorn D, Weghorn D.   +4 more
europepmc   +1 more source

CDK-independent role of D-type cyclins in regulating DNA mismatch repair. [PDF]

Mol Cell
Rona G, Miwatani-Minter B, Zhang Q, Goldberg HV, Kerzhnerman MA, Howard JB, Simoneschi D, Lane E, Hobbs JW, Sassani E, Wang AA, Keegan S, Laverty DJ, Piett CG, Pongor LS, Xu ML, Andrade J, Thomas A, Sicinski P, Askenazi M, Ueberheide B, Fenyö D, Nagel ZD, Pagano M.   +23 more
europepmc   +1 more source

Allometric Scaling in Environmental DNA Concentration of Japanese Eel Anguilla japonica Confirmed Under Laboratory and Natural Conditions 日本鳗 (Anguilla japonica) 环境 DNA 浓度中的异速生长标度在实验室和自然条件下得到证实

Integrative Conservation, EarlyView.
We demonstrated that Anguilla japonica eDNA concentration was allometrically scaled with their body size in both the laboratory and riverine environments. Integrating body size allometry has the potential to improve population abundance estimates in the field, whereas further clarification is required for understanding eDNA production mechanisms ...
Toshiaki S. Jo, Aya Takeuchi, Hikaru Itakura   +2 more
wiley   +1 more source

PD-1 blockade combined with chemotherapy and bevacizumab in DNA mismatch repair-proficient/microsatellite stable colorectal liver metastases. [PDF]

J Gastrointest Oncol
Men Q, Duan Y, Pei F, Yao Q, He W, Zhao Y, Shi L, Liu G, Huang J.   +8 more
europepmc   +1 more source

Altered Replication and Inverted Repeats Induce Mismatch Repair-Independent Recombination between Highly Diverged DNAs in Yeast

, 1997
Hiep T. Tran, Natasha P. Degtyareva, Dmitry A. Gordenin, Michael A. Resnick   +3 more
openalex   +2 more sources

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Response to immune checkpoint inhibition in a meningioma with DNA mismatch repair deficiency. [PDF]

Neurooncol Adv
Nguyen MP, Almiron Bonnin D, Mirchia K, Chen WC, Goldschmidt E, Braunstein SE, Perry A, Raleigh DR, Oberheim Bush NA.   +8 more
europepmc   +1 more source

Microsatellite Instability and DNA Mismatch Repair Protein Deficiency in Lynch Syndrome Colorectal Polyps

, 2012
Matthew B. Yurgelun, Ajay Goel, Jason L. Hornick, Ananda Sen, D. Kim Turgeon, Mack T. Ruffin, Norman E. Marcon, John A. Baron, Robert S. Bresalier, Sapna Syngal, Dean E. Brenner, C. Richard Boland, Elena M. Stoffel   +12 more
openalex   +2 more sources