Results 51 to 60 of about 6,763 (148)

Genomic surveillance of Neisseria gonorrhoeae to investigate the distribution and evolution of antimicrobial-resistance determinants and lineages [PDF]

, 2018
The first extensively drug resistant (XDR) Neisseria gonorrhoeae strain with high resistance to the extended-spectrum cephalosporin ceftriaxone was identified in 2009 in Japan, but no other strain with this antimicrobial-resistance profile has been ...
Deguchi, Takashi, Didelot, Xavier, Kawahata, Takuya, Kuroki, Toshiro, Lee, Ken-ichi, Morita, Masatomo, Nakayama, Shu-ichi, Ohnishi, Makoto, Ohya, Hitomi, Shimuta, Ken, Watanabe, Yuko, Yahara, Koji, Yasuda, Mitsuru   +12 more
core   +1 more source

Antimicrobial Susceptibility Profile of Escherichia coli Isolates From Artisanal Colonial Cheese in Southern Brazil

Food Safety and Health, Volume 3, Issue 4, Page 659-667, October 2025.
This study evaluated the antimicrobial susceptibility profile of Escherichia coli isolated from artisanal colonial cheese from Brazil. Sixty percent of the isolates showed resistance to at least one antimicrobial, no ESBL was found, genes blaTEM and tetB were found simultaneously in four isolates.
Luísa Aimée Schmitt Lobe, Vanessa Cortina Zanetti, Natália Regina Coldebella Ferreira, Matheus Viapiana Frutuoso, Isadora Caroline Marian, Emanueli Marchesan Maran, Manuela Maggiora Freitas Bastos, Julia Eduarda Munaretto, Gustavo Rocha, Mateus Rocha Ribas, Victor Felipe Wolleck, Francisco Lucas Amorim Nascimento, Jussara Kasuko Palmeiro, Marília Miotto‐Lindner, Silvani Verruck   +14 more
wiley   +1 more source

Unusual tRNA nucleotidyltransferases: Adaptation of the Romanomermis culicivorax CCA-adding enzyme towards armless tRNAs and characterization of the phosphodiesterase domain of the Escherichia coli CCA-adding enzyme [PDF]

, 2022
tRNAs spielen eine zentrale Rolle in jedem bekannten Organismus. Sie agieren als Adaptoren, um den Code der Nukleinsäuren in eine funktionale Aminosäuresequenz zu übersetzen.
Philipp, Susanne
core   +1 more source

The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
Analysis of Acinetobacter baumannii from healthy individuals in a rural Malaysian community revealed significant genetic diversity, including novel sequence types. These isolates carry resistance genes and resemble clinical strains, highlighting their potential to cause disease despite their commensal origin.
Soo‐Sum Lean, Denise E. Morris, Rebecca Anderson, Ahmed Ghazi Alattraqchi, David W. Cleary, Stuart C. Clarke, Chew Chieng Yeo   +6 more
wiley   +1 more source

Discovery of Three Toxic Proteins of Klebsiella Phage fHe-Kpn01 [PDF]

, 2020
The lytic phage, fHe-Kpn01 was isolated from sewage water using an extended-spectrum beta-lactamase-producing strain of Klebsiella pneumoniae as a host. The genome is 43,329 bp in size and contains direct terminal repeats of 222 bp.
Pajunen, Maria I., Skurnik, Mikael, Spruit, Cindy M., Wan, Xing, Wicklund, Anu   +4 more
core   +3 more sources

TENT5C functions as a corepressor in the ligand‐bound glucocorticoid receptor and estrogen receptor α complexes

The FEBS Journal, Volume 292, Issue 19, Page 5168-5184, October 2025.
TENT5C is a suppressor of ERα and GR transcriptional activation. A specific LXXLL motif in TENT5C, absent in the other members of the TENT5 subfamily, mediates a stable interaction with the Ligand Binding Domain of ERα but not with that of GR.
Yin Li, Lalith Perera, Rebecca S. He, Marine Baptissart, Robert M. Petrovich, Marcos Morgan   +5 more
wiley   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, Volume 599, Issue 18, Page 2674-2684, September 2025.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Viroids: Survivors from the RNA World? [PDF]

, 2014
Because RNA can be a carrier of genetic information and a biocatalyst, there is a consensus that it emerged before DNA and proteins, which eventually assumed these roles and relegated RNA to intermediate functions.
Flores, Ricardo, Gago, Selma, Sanjuán, Rafael, Serra, Pedro   +3 more
core   +1 more source

Comprehensive Pan‐Cancer Analysis of TRNT1 as a Potential Biomarker for Breast Cancer

Journal of Cellular and Molecular Medicine, Volume 29, Issue 18, September 2025.
ABSTRACT TRNT1, an RNA nucleotide transferase, plays a critical role in cellular processes and may be involved in cancer. However, its role in cancer has not been fully explored. This study aims to explore the potential significance of TRNT1 in cancer, particularly in breast cancer (BC) progression and prognosis.
Xinwei Li, Yue Meng, Bing Gu
wiley   +1 more source

Stress alters hypothalamic gene expression in adolescent male Golden hamsters

Journal of Neuroendocrinology, Volume 37, Issue 9, September 2025.
Abstract In Golden hamsters (Mesocricetus auratus), a two‐week exposure to chronic social stress in adolescence causes acceleration of agonistic behavior, enhanced adult aggression, impaired waiting impulsivity, and higher food intake, body fat, and long‐term increased body weight.
Kevin M. Moran, Tyler M. Milewski, James P. Curley, Yvon Delville   +3 more
wiley   +1 more source