Results 71 to 80 of about 6,866 (163)

A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression [PDF]

open access: yes, 2017
The p.N478D missense mutation in human mitochondrial poly(A) polymerase (mtPAP) has previously been implicated in a form of spastic ataxia with optic atrophy. In this study, we have investigated fibroblast cell lines established from family members.
Baslé, Arnaud   +17 more
core  

THE IDENTIFICATION OF NOVEL INORGANIC CARBON SENSITIVE ENZYMES [PDF]

open access: yes, 2010
Adenylyl cyclase catalyses the formation of the second messenger adenosine-3’, 5’-monophosphate from adenosine triphosphate, and is involved in a number of diverse signalling pathways in eukaryotes and prokaryotes.
TOWNSEND, PHILIP,DAVID
core  

Biophysical and biochemical characterization of yeast tRNA nucleotidyltransferase variants [PDF]

open access: yes, 2017
The enzyme ATP(CTP):tRNA-specific tRNA nucleotidyltransferase adds cytidine-cytidine-adenosine (CCA) to the 3’ end of eukaryotic tRNAs during their maturation. This CCA sequence plays a vital role in aminoacylation and hence in protein synthesis.
Rahman, Mohammed Samiur
core  

A LC-MS/MS-Based Approach to Studying the Saccharomyces cerevisiae Cca1 Protein [PDF]

open access: yes, 2018
The enzyme ATP (CTP): tRNA-specific tRNA nucleotidyltransferase (tRNA-NT) is an essential enzyme in eukaryotes and some prokaryotes and plays a critical role in tRNA maturation. This enzyme is responsible for the addition of AMP and CMP residues to the 3’
Guan, Tian Lai
core  

The identity of the discriminator base has an impact on CCA addition [PDF]

open access: yes, 2015
CCA-adding enzymes synthesize and maintain the C-C-A sequence at the tRNA 3''-end, generating the attachment site for amino acids. While tRNAs are the most prominent substrates for this polymerase, CCA additions on non-tRNA transcripts are described as ...
Betat, Heike   +4 more
core   +1 more source

Inhibition of reverse transcriptases by seminalplasmin [PDF]

open access: yes, 1983
Seminalplasmin, an antibacterial protein present in bovine seminal plasma, is shown to be a potent inhibitor of reverse transcriptases (RNA-dependent DNA nucleotidyltransferases).
Reddy, E. S.   +3 more
core  

Divergent Evolution of Eukaryotic CC- and A-Adding Enzymes [PDF]

open access: yes
Synthesis of the CCA end of essential tRNAs is performed either by CCA-adding enzymes or as a collaboration between enzymes restricted to CC- and A-incorporation. While the occurrence of such tRNA nucleotidyltransferases with partial activities seemed to
Betat, Heike   +4 more
core   +1 more source

Bicuculline reversal of aminoglycoside O-nucleotidyltransferase EanT-1-mediated kanamycin resistance. [PDF]

open access: yesBMC Microbiol
Wang J   +8 more
europepmc   +1 more source

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