Biological Activity of the phenylethanol and its derivatives. Influence on isolated DNA nucleotidyltransferase and DNAase [PDF]
Müller, W.E.G. +4 more
openaire +2 more sources
A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression [PDF]
The p.N478D missense mutation in human mitochondrial poly(A) polymerase (mtPAP) has previously been implicated in a form of spastic ataxia with optic atrophy. In this study, we have investigated fibroblast cell lines established from family members.
Baslé, Arnaud +17 more
core
THE IDENTIFICATION OF NOVEL INORGANIC CARBON SENSITIVE ENZYMES [PDF]
Adenylyl cyclase catalyses the formation of the second messenger adenosine-3’, 5’-monophosphate from adenosine triphosphate, and is involved in a number of diverse signalling pathways in eukaryotes and prokaryotes.
TOWNSEND, PHILIP,DAVID
core
Biophysical and biochemical characterization of yeast tRNA nucleotidyltransferase variants [PDF]
The enzyme ATP(CTP):tRNA-specific tRNA nucleotidyltransferase adds cytidine-cytidine-adenosine (CCA) to the 3’ end of eukaryotic tRNAs during their maturation. This CCA sequence plays a vital role in aminoacylation and hence in protein synthesis.
Rahman, Mohammed Samiur
core
A LC-MS/MS-Based Approach to Studying the Saccharomyces cerevisiae Cca1 Protein [PDF]
The enzyme ATP (CTP): tRNA-specific tRNA nucleotidyltransferase (tRNA-NT) is an essential enzyme in eukaryotes and some prokaryotes and plays a critical role in tRNA maturation. This enzyme is responsible for the addition of AMP and CMP residues to the 3’
Guan, Tian Lai
core
The identity of the discriminator base has an impact on CCA addition [PDF]
CCA-adding enzymes synthesize and maintain the C-C-A sequence at the tRNA 3''-end, generating the attachment site for amino acids. While tRNAs are the most prominent substrates for this polymerase, CCA additions on non-tRNA transcripts are described as ...
Betat, Heike +4 more
core +1 more source
Inhibition of reverse transcriptases by seminalplasmin [PDF]
Seminalplasmin, an antibacterial protein present in bovine seminal plasma, is shown to be a potent inhibitor of reverse transcriptases (RNA-dependent DNA nucleotidyltransferases).
Reddy, E. S. +3 more
core
Divergent Evolution of Eukaryotic CC- and A-Adding Enzymes [PDF]
Synthesis of the CCA end of essential tRNAs is performed either by CCA-adding enzymes or as a collaboration between enzymes restricted to CC- and A-incorporation. While the occurrence of such tRNA nucleotidyltransferases with partial activities seemed to
Betat, Heike +4 more
core +1 more source
Dysregulation of a nucleotidyltransferase induces division and surface glycan defects in <i>Escherichia coli</i> by altering related metabolite levels. [PDF]
Zheng MC +6 more
europepmc +1 more source
Bicuculline reversal of aminoglycoside O-nucleotidyltransferase EanT-1-mediated kanamycin resistance. [PDF]
Wang J +8 more
europepmc +1 more source

