Results 81 to 90 of about 894,362 (295)
White Spot Syndrome Virus Orf514 Encodes a Bona Fide DNA Polymerase
Molecules, 2011 White spot syndrome virus (WSSV) is the causative agent of white spot syndrome, one of the most devastating diseases in shrimp aquaculture. The genome of WSSV includes a gene that encodes a putative family B DNA polymerase (ORF514), which is 16 ...
Rogerio R. Sotelo-Mundo +7 more
doaj +1 more source
Effects of cations on DNA-dependent RNA polymerase. [PDF]
, 1967 Antero G. So +3 more
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Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
COMPARISON OF SIX COMMERCIALLY-AVAILABLE DNA POLYMERASES FOR DIRECT PCR
Revista do Instituto de Medicina Tropical de São Paulo, 2013 SUMMARY The use of a “direct PCR” DNA polymerase enables PCR amplification without any prior DNA purification from blood samples due to the enzyme's resistance to inhibitors present in blood components. Such DNA polymerases are now commercially available.
Masashi Miura +3 more
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DNA polymerase in isolated tobacco chloroplasts and nature of the polymerized product. [PDF]
, 1967 Κ. Κ. Tewari, S. G. Wildman
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Macedonian Journal of Chemistry and Chemical Engineering, 2017 Тhermophilic bacteria Bacillus caldolyticus isolated from the hot spring in Bansko, Republic of Macedonia, were used for the isolation of DNA polymerase.
Zoran T Popovski +3 more
doaj +1 more source
RIBONUCLEIC ACID POLYMERASE OF AZOTOBACTER VINELANDII, II. FORMATION OF DNA-RNA HYBRIDS WITH SINGLE-STRANDED DNA AS PRIMER [PDF]
, 1963 Robert C. Warner +3 more
openalex +1 more source