Results 91 to 100 of about 1,931,156 (311)

4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study. [PDF]

, 2010
In Caucasian patients with severe sepsis due to pneumonia carriers of the 4G allele of PAI-1 polymorphism have higher risk for multiple organ dysfunction syndrome and septic shock and in agreement they showed more fulminant disease progression based on ...
Aladzsity, István, Prohászka Zoltán, Madách Krisztina, Füst György, Pénzes, István, Gál János, Pénzes István, Madách, Krisztina, Prohászka, Zoltán, Szilágyi Ágnes, Aladzsity István, Szilágyi, Agnes, Fust, George, Gál, János   +13 more
core   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Investigations into the molecular effects of single nucleotide polymorphism [PDF]

, 2000
Objectives: DNA sequences are very rich in short repeats and their pattern can be altered by point mutations. We wanted to investigate the effect of single nucleotide polymorphism (SNP) on the pattern of short DNA repeats and its biological consequences.
Lohrer, Horst D., Tangen, Uwe, Lohrer, H.D., Tangen, U.   +3 more
core   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

DNA banding pattern polymorphism in vancomycin-resistant Enterococcus faecium and criteria for defining strains.

, 1999
The degree of DNA banding pattern polymorphism exhibited by vancomycin-resistant Enterococcus faecium (VREM) strains isolated on a renal unit over an 11-month period was investigated.
Barrett, S P, Sisson, P, Morrison, Donald, Cookson, B D, Woodford, N   +4 more
core  

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Molecular characterization of Cryptosporidium isolates from humans and other animals using random amplified polymorphic DNA analysis [PDF]

, 1995
Genetic variation in 25 Cryptosporidium isolates was analyzed using the random amplified polymorphic DNA (RAPD) technique. Simple reproducible polymorphisms were generated (using five primers) from Cryptosporidium DNA that was free of contaminating ...
O'Donoghue, P., Meloni, BP, Meloni, B.P., Morgan, UM, Thompson, R.C.A., Morgan, U.M., R. C. Andrew Thompson, Peter O'Donoghue, Constantine, CC, Philip A. O'Brien, Clare C. Constantine, Constantine, C.C., Odonoghue, P, Obrien, PA, O'Brien, P.A., Bruno P. Meloni, Thompson, Rca, Una M. Morgan   +17 more
core   +1 more source

Synthesis and Characterization of Biocompatible Manganese‐Doped Titania Nanoparticles and Its Application to Single‐Cell Nanoencapsulation

Advanced Materials Interfaces, EarlyView.
Biocompatible Mn‐doped TiO2 nanozymes integrate TiO2 stability with Mn redox activity, enabling dopamine‐mediated cell‐surface polymerization and single‐cell nanoencapsulation while maintaining high colloidal stability, low ROS generation, and excellent cellular compatibility.
Filip Kozłowski, Nayoung Kim, Hyunwoo Choi, Geoffrey Daniel, Gulaim A. Seisenbaeva, Insung S. Choi, Vadim G. Kessler   +6 more
wiley   +1 more source

Mitochondrial DNA Polymorphism in HV1 and HV2 Regions and 12S rDNA in Perimenopausal Hypertensive Women. [PDF]

Biomedicines, 2023
Kwaśniewski W, Stupak A, Warowicka A, Goździcka-Józefiak A, Mosiewicz J, Mieczkowska J.   +5 more
europepmc   +1 more source

Genetic relatedness in different Medicago sativa lines based on polymorphism of mitochondrial DNA specific sequences

, 2010
Two synthetic populations (Syn-5 and Syn-7), four inbred lines and four landraces of alfalfa (Medicago sativa L.) were studied for genetic relatedness. These forms were characterized by different amount of seeds set and green mass yield. Two primer pairs
L. Skuza, S. M. Dyba, S. M. Rogalska
core   +1 more source