Results 11 to 20 of about 3,796,516 (329)
Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA
Molecules, 2022 The development of chemically modified oligonucleotides enabling robust, sequence-unrestricted recognition of complementary chromosomal DNA regions has been an aspirational goal for scientists for many decades.
Caroline P. Shepard +3 more
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Nanophotonics, 2023 This study proposes and demonstrates a novel label-free DNA biosensor using high quality optical microcavity functionalized by 3D DNA nanostructure probes. To achieve ultra-low limit DNA biosensing, optical sensing interface of the hollow-core, thin wall-
Wan Hongdan +6 more
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Probing the Mechanical Unzipping of DNA [PDF]
Physical Review Letters, 2006 A study of the micromechanical unzipping of DNA in the framework of the Peyrard-Bishop-Dauxois model is presented. We introduce a Monte Carlo technique that allows accurate determination of the dependence of the unzipping forces on unzipping speed and temperature. Our findings agree quantitatively with experimental results for homogeneous DNA, and for $
Kim Ø. Rasmussen +3 more
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Probing Allostery Through DNA [PDF]
Science, 2013 Allostery Across DNA Proteins, such as transcription factors and RNA polymerase, bind close to each other on DNA and their function is coordinated. Kim et al. (p. 816 ; see the Perspective by Crothers
Yujie Sun +13 more
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A Bioorthogonal Double Fluorogenic Probe to Visualize Protein–DNA Interaction
Chemosensors, 2022 Two sets of bioorthogonally applicable, double fluorogenic probes, capable of sensing DNA–protein interactions, were prepared by installing an azide or tetrazine motif onto structurally fluorogenic, DNA sensitive frames.
Attila Kormos +7 more
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Definitions, 2020 Facioscapulohumeral (Landouzy-Dejerine) disease (FSHD), with a prevalence estimated at 5/100 0o0,1 2 is arguably one of the more common inherited neuromuscular disorders.
M. Upadhyaya +4 more
semanticscholar +1 more source
Вавиловский журнал генетики и селекции, 2020 The free-living flatworm Macrostomum mirumnovem is a neopolyploid species whose genome underwent a recent Whole Genome Duplication (WGD). In the result of chromosome fusions of the ancient haploid chromosome set, large metacentric chromosomes were formed.
K. S. Zadesenets, N. B. Rubtsov
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Discovered Key CpG Sites by Analyzing DNA Methylation and Gene Expression in Breast Cancer Samples
Frontiers in Cell and Developmental Biology, 2022 Breast cancer is the most common cancer in the world, and DNA methylation plays a key role in the occurrence and development of breast cancer. However, the effect of DNA methylation in different gene functional regions on gene expression and the effect ...
Yan-Ni Cao +3 more
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Fluorescent Probes of DNA Repair [PDF]
ACS Chemical Biology, 2017 DNA repair is now understood to play a key role in a variety of disease states, most notably cancer. Tools for studying DNA have typically relied on traditional biochemical methods which are often laborious and indirect. Efforts to study the biology and therapeutic relevance of DNA repair pathways can be limited by such methods.
David L. Wilson, Eric T. Kool
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Neuropsychopharmacology Reports, 2020 Background Commercially available Illumina DNA methylation arrays (HumanMethylation 27K, HumanMethylation450, and MethylationEPIC BeadChip) can be used for comprehensive DNA methylation analyses of not only the human genome but also other mammalian ...
Yutaka Nakachi +4 more
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