Results 191 to 200 of about 792,120 (349)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Targeted DNA Methylation Using Modified DNA Probes: A Potential Therapeutic Tool for Depression and Stress-Related Disorders. [PDF]

Int J Mol Sci
Modi N, Guo J, Lee RA, Greenstein A, Lee RS.   +4 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Sorting Extrusion-Prepared Coreless Cell Membrane Vesicles of Mixed Orientations by Functional DNA Probes. [PDF]

JACS Au
Ye J, Xu F, Xu Z, Yuan C, Hou P, Wu D, Han W, Pan S, Pan L, Yang D, Wang P.   +10 more
europepmc   +1 more source

Analysis of Single Nucleotide-Mutated Single-Cancer Cells Using the Combined Technologies of Single-Cell Microarray Chips and Peptide Nucleic Acid-DNA Probes. [PDF]

Micromachines (Basel), 2020
Shigeto H, Yamada E, Kitamatsu M, Ohtsuki T, Iizuka A, Akiyama Y, Yamamura S.   +6 more
europepmc   +1 more source

Probing Evolutionary Patterns in Neotropical Birds through DNA Barcodes

, 2009
Kevin C. R. Kerr, Darío A. Lijtmaer, Ana S. Barreira, Paul D. N. Hebert, Pablo L. Tubaro   +4 more
openalex   +2 more sources

HPV DNA Probes [PDF]

, 2020
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Generation of microdissected DNA probes from metaphase chromosomes when chromosome identification by routine staining is impossible. [PDF]

Vavilovskii Zhurnal Genet Selektsii, 2020
Zadesenets KS, Rubtsov NB.
europepmc   +1 more source

Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins

, 2015
Dmytro Dziuba, Radek Pohl, Michal Hocek
openalex   +2 more sources