Results 21 to 30 of about 3,869,166 (380)
Fluorescence in situ hybridization of YAC clones after Alu-PCR amplification [PDF]
, 1992 Alu-PCR protocols were optimized for the generation of human DNA probes from yeast strains containing yeast artificial chromosomes (YACs) with human inserts between 100 and 800 kb in size.
Brooks-Wilson +15 more
core +1 more source
Molecules, 2015 Development of probes that allow for sequence-unrestricted recognition of double-stranded DNA (dsDNA) continues to attract much attention due to the prospect for molecular tools that enable detection, regulation, and manipulation of genes.
Brooke A. Anderson +2 more
doaj +1 more source
A cellulose-based bioassay for the colorimetric detection of pathogen DNA [PDF]
, 2014 Cellulose-paper-based colorimetric bioassays may be used at the point of sampling without sophisticated equipment. This study reports the development of a colorimetric bioassay based on cellulose that can detect pathogen DNA.
Goyal, Madhu +3 more
core +1 more source
Fluorescent Probes of DNA Repair [PDF]
ACS Chemical Biology, 2017 DNA repair is now understood to play a key role in a variety of disease states, most notably cancer. Tools for studying DNA have typically relied on traditional biochemical methods which are often laborious and indirect. Efforts to study the biology and therapeutic relevance of DNA repair pathways can be limited by such methods.
David L. Wilson, Eric T. Kool
openaire +2 more sources
Sensors, 2009 In the present study we describe sandwich design hybridization probes consisting of magnetic particles (MP) and quantum dots (QD) with target DNA, and their application in the detection of avian influenza virus (H5N1) sequences. Hybridization of 25-, 40-,
Alexey Dan Chin Yu +4 more
doaj +1 more source
Electrochemical detection of the toxic dinoflagellate Alexandrium ostenfeldii with a DNA-biosensor [PDF]
, 2005 The steady rise of observations of harmful or toxic algal blooms throughout the world in the past decades constitute a menace for coastal ecosystems and human interests.
Huljic, S. +3 more
core +1 more source
Development and application of DNA molecular probes
AIMS Bioengineering, 2017 The development of DNA probes started from 1950's for diagnostic purposes and it is still growing. DNA probes are applied in several fields such as food, medical, veterinary, environment and security, with the aim of prevention, diagnosis and treatment ...
Priya Vizzini +3 more
doaj +1 more source
Nucleic Acids Research, 2016 Illumina Infinium DNA Methylation BeadChips represent the most widely used genome-scale DNA methylation assays. Existing strategies for masking Infinium probes overlapping repeats or single nucleotide polymorphisms (SNPs) are based largely on ad hoc ...
Wanding Zhou, P. Laird, Hui Shen
semanticscholar +1 more source
Electrically Guided DNA Immobilization and Multiplexed DNA Detection with Nanoporous Gold Electrodes. [PDF]
, 2018 Molecular diagnostics have significantly advanced the early detection of diseases, where the electrochemical sensing of biomarkers (e.g., DNA, RNA, proteins) using multiple electrode arrays (MEAs) has shown considerable promise.
Daggumati, Pallavi +3 more
core +3 more sources
Fluorescent DNA hybridization probe preparation using amine modification and reactive dye coupling
BioTechniques, 2004 Fluorescent nucleic acid hybridization probes traditionally have been generated by enzymatic incorporation of dye-labeled nucleotides, even though incorporation efficiency is low and variable from dye to dye.
W. Gregory Cox, Victoria L. Singer
doaj +1 more source