Results 351 to 360 of about 3,927,360 (403)

Mimicking an Enzyme-Based Colorimetric Aptasensor for Antibiotic Residue Detection in Milk Combining Magnetic Loop-DNA Probes and CHA-Assisted Target Recycling Amplification.

Journal of Agricultural and Food Chemistry, 2017
A mimicking-enzyme-based colorimetric aptasensor was developed for the detection of kanamycin (KANA) in milk using magnetic loop-DNA-NMOF-Pt (m-L-DNA) probes and catalytic hairpin assembly (CHA)-assisted target recycling for signal amplification. The m-L-
Qian Luan, Ning Gan, Yuting Cao, Tianhua Li   +3 more
semanticscholar   +1 more source

Highly sensitive and selective detection of miRNA: DNase I-assisted target recycling using DNA probes protected by polydopamine nanospheres.

Chemical Communications, 2015
Based on the protective properties of polydopamine nanospheres for DNA probes against nuclease digestion, we have developed a DNase I-assisted target recycling signal amplification method for highly sensitive and selective detection of miRNA.
Yi Xie, Xiaoyan Lin, Yishun Huang, Rujun Pan, Zhi Zhu, Leiji Zhou, C. Yang   +6 more
semanticscholar   +1 more source

Multicolor Gold-Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection.

Analytical Chemistry, 2017
Uniform silver-containing metal nanostructures with strong and stable surface-enhanced Raman scattering (SERS) signals hold great promise for developing ultrasensitive probes for biodetection.
Jing Su, Dongfang Wang, Lena Nörbel, Jianlei Shen, Zhihan Zhao, Yanzhi Dou, Tianhuan Peng, Jiye Shi, S. Mathur, C. Fan, Shiping Song   +10 more
semanticscholar   +1 more source

DNA Clutch Probes for Circulating Tumor DNA Analysis.

Journal of the American Chemical Society, 2016
Progress toward the development of minimally invasive liquid biopsies of disease is being bolstered by breakthroughs in the analysis of circulating tumor DNA (ctDNA): DNA released from cancer cells into the bloodstream.
J. Das, Ivaylo K. Ivanov, E. Sargent, S. Kelley   +3 more
semanticscholar   +1 more source

Hairpin DNA probes based on target-induced in situ generation of luminescent silver nanoclusters.

Chemical Communications, 2014
Novel hairpin DNA probes are designed and constructed based on target-induced in situ generation of luminescent silver nanoclusters. This design allows specific and versatile detection of diverse targets with easy operation and low cost.
Yan Xiao, Zhengjun Wu, Kwok-Yin Wong, Zhihong Liu   +3 more
semanticscholar   +1 more source

Scanometric DNA array detection with nanoparticle probes.

Science, 2000
A method for analyzing combinatorial DNA arrays using oligonucleotide-modified gold nanoparticle probes and a conventional flatbed scanner is described here.
T. Taton, C. Mirkin, R. Letsinger
semanticscholar   +1 more source

A graphene-based biosensing platform based on the release of DNA probes and rolling circle amplification.

ACS Nano, 2014
We report a versatile biosensing platform capable of achieving ultrasensitive detection of both small-molecule and macromolecular targets. The system features three components: reduced graphene oxide for its ability to adsorb single-stranded DNA ...
Meng Liu, Jinping Song, S. Shuang, C. Dong, J. Brennan, Yingfu Li   +5 more
semanticscholar   +1 more source

DNA probes and automation

Current Biology, 1992
Current methods for DNA probe analysis in principle provide access to the total genetic information of any organism and permit applications in health care, for example. In practice, however, greatly improved efficiency of methods for decoding genetic information is required for both research and routine applications.
openaire   +4 more sources

Probing Mouse Origins with Random DNA Probes

1988
Until not so long ago, many villages and towns used to have their own chroniclers who took it upon themselves to record for posterity those events which they believed to be the most important in the life of the community. They were, of course, no professionals; they were farmers, bakers, shoemakers, or pursued whatever occupation happened to be in ...
Masanori Kasahara, Vladimir Vincek, Jan Klein, Jan Klein, Felipe Figueroa   +4 more
openaire   +3 more sources

Multiplex ligation-dependent probe amplification (MLPA) for ultrasensitive multiplexed microRNA detection using ribonucleotide-modified DNA probes.

Chemical Communications, 2013
Using the ribonucleotide-modified DNA probes, multiple microRNAs can be simultaneously detected in one ligation-based PCR reaction. As low as 0.2 fM microRNA can be accurately detected with high specificity.
Pengbo Zhang, Ye Liu, Yajing Zhang, Chenghui Liu, Zhibin Wang, Zhengping Li   +5 more
semanticscholar   +1 more source