Results 231 to 240 of about 5,488,409 (376)

The Gene Expression Profile of Human Umbilical Vein Endothelial Cells Stimulated by Tumor Necrosis Factor a Using DNA Microarray Analysis

, 2000
Takeshi Murakami, Chikage Mataki, Chizuru Nagao, Michihisa Umetani, Y Wada, Masami Ishii, Shuichi Tsutsumi, Takahide Kohro, Akio Saiura, Hiroyuki Aburatani, Takao Hamakubo, Tatsuhiko Kodama   +11 more
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Detection of Tumor Recurrence via Circulating Tumor DNA Profiling in Patients with Localized Lung Cancer: Clinical Considerations and Challenges. [PDF]

Cancers (Basel), 2021
Ulrich B, Pradines A, Mazières J, Guibert N.   +3 more
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Comprehensive analysis of PIK3CA mutations in advanced colorectal cancer using circulating tumor DNA profiling. [PDF]

NPJ Precis Oncol
Milsap A, Tsai J, Jafry B, Kim A, Ali Kazmi SM, Verma N.   +5 more
europepmc   +1 more source

DNA profiling and assessment of genetic diversity of relict species Allium altaicum Pall. on the territory of Altai. [PDF]

PeerJ, 2021
Khapilina O, Raiser O, Danilova A, Shevtsov V, Turzhanova A, Kalendar R.   +5 more
europepmc   +1 more source

Breast cancer revisited using DNA array‐based gene expression profiling [PDF]

, 2002
François Bertucci, Patrice Viens, Pascal Hingamp, Valéry Nasser, Rémi Houlgatte, Daniel Birnbaum   +5 more
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Use of DNA profiling to resolve HIV status in a person using injectable cabotegravir for HIV pre-exposure prophylaxis. [PDF]

J Clin Pathol
Fogel JM, Salih MA, Haddaway K, Marzinke MA, Marshall C, Wang Z, Cummings V, Piwowar-Manning E, Rooney JF, McCauley M, Grinsztejn B, Landovitz RJ, Eshleman SH.   +12 more
europepmc   +1 more source

DNA microarray analysis of the expression profiles of luteinized granulosa cells as a function of ovarian reserve [PDF]

, 2002
Khew‐Voon Chin, David B. Seifer, Bo Feng, Yong Lin, Wei-Chung Shih   +4 more
openalex   +1 more source