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DNA in profile

Trends in Biochemical Sciences, 1991
The double helix structure of DNA is not necessarily straight but rather can be curved at almost every base pair. Thus, each piece of DNA possesses a unique silhouette, as individual as its base sequence.
openaire   +2 more sources

DNA profiling of Shahtoosh

ELECTROPHORESIS, 2006
AbstractThe population of the Tibetan Antelope (Pantholops hodgsonii) has recently declined dramatically due to the illegal trade in its wool. The animal lives at high altitude and is protected from the extremely cold climate due to a coat of very fine wool. These hairs are highly sought for weaving a shawl called shahtoosh. The large‐scale poaching of
Linacre, A.M.T.   +7 more
openaire   +3 more sources

Chimpanzee DNA profiles on trial

Nature, 1994
No abstract ...
V. L. Pascali   +5 more
openaire   +6 more sources

DNA reviews: low level DNA profiling

Forensic Science, Medicine, and Pathology, 2008
Low copy number (LCN) DNA profiling has recently been scrutinized in the United Kingdom following the comments of Mr Justice Weir made during the trial of suspected terrorist Sean Hoey. Mr Hoey was acquitted of all charges related to the Omagh bombing of 1998, following the inadmissibility of key DNA evidence during this trial. The Association of Chief
openaire   +2 more sources

Automated DNA Profile Analysis

Forensic Science, Medicine, and Pathology, 2005
DNA profile analysis is not a simple process. Stringent demands are placed on the accuracy and consistency of forensic evidence so that complex, robust, and reproducible guidelines are necessary to assist the analyst and ensure mistakes are eliminated before a final profile is reported.
openaire   +2 more sources

Composite profiles in DNA analysis

Forensic Science International: Genetics, 2012
Composite profiles are created by combining DNA profiling information from replicate profiles derived from the same DNA extract. In this paper we have shown that, provided the probability of drop-in is low or nil, the creation of composite profiles is an acceptable approximation to a Bayesian approach, as long as simple samples are analysed.
Jo-Anne, Bright   +2 more
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DNA methylation profiling in cancer

Expert Reviews in Molecular Medicine, 2010
Aberrant DNA methylation in the genome is found in almost all types of cancer and contributes to malignant transformation by silencing multiple tumour-suppressor genes, sometimes simultaneously. Therefore, deciphering the signature of DNA methylation in each tumour is required to better understand tumour behaviour and might be of benefit for clinical ...
Yutaka, Kondo, Jean-Pierre J, Issa
openaire   +2 more sources

Genome‐wide DNA methylation profiling

WIREs Systems Biology and Medicine, 2009
AbstractDNA methylation plays a critical role in the regulation of gene expression. The ability to access the methylation status for a large number of genes or the entire genome should greatly facilitate the understanding of the nature of gene regulation in cells, and epigenetic mechanism of interactions between cells and environment.
Marina, Bibikova, Jian-Bing, Fan
openaire   +2 more sources

Interpreting low template DNA profiles

Forensic Science International: Genetics, 2009
We discuss the interpretation of DNA profiles obtained from low template DNA samples. The most important challenge to interpretation in this setting arises when either or both of "drop-out" and "drop-in" create discordances between the crime scene DNA profile and the DNA profile expected under the prosecution allegation.
David J, Balding, John, Buckleton
openaire   +2 more sources

DNA Profiling and DNA Fingerprinting

1999
1. DNA Fingerprinting of Prokaryotic Genomes.- 2. Plant DNA Fingerprinting and Profiling.- 3. DNA Fingerprinting and Profiling in Behavioural Ecology.- 4. DNA Profiling in Veterinary Medicine.- 5. Multilocus DNA Fingerprinting.- 6. Various Levels of (Epi)Genetic Diversities as Demonstrable via Simple Repeated Sequences.- 7. Forensics: Analysis of Short
openaire   +1 more source

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