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Proceedings of the 1st International Conference on Algorithms, Computing and Systems, 2017
Identification of individual STR-based individuals is required for the investigation of Disaster Victim Identification and other applications. The DNA identification of an individual with the DNA of both biological parents, father, and mother, would result in a perfect match value, but what if the biological parents of the individual had died.
Maria Susan Anggreainy +2 more
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Identification of individual STR-based individuals is required for the investigation of Disaster Victim Identification and other applications. The DNA identification of an individual with the DNA of both biological parents, father, and mother, would result in a perfect match value, but what if the biological parents of the individual had died.
Maria Susan Anggreainy +2 more
openaire +2 more sources
Composite profiles in DNA analysis
Forensic Science International: Genetics, 2012Composite profiles are created by combining DNA profiling information from replicate profiles derived from the same DNA extract. In this paper we have shown that, provided the probability of drop-in is low or nil, the creation of composite profiles is an acceptable approximation to a Bayesian approach, as long as simple samples are analysed.
Jo-Anne Bright +3 more
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DNA methylation profiling in cancer
Expert Reviews in Molecular Medicine, 2010Aberrant DNA methylation in the genome is found in almost all types of cancer and contributes to malignant transformation by silencing multiple tumour-suppressor genes, sometimes simultaneously. Therefore, deciphering the signature of DNA methylation in each tumour is required to better understand tumour behaviour and might be of benefit for clinical ...
Jean Pierre J. Issa, Yutaka Kondo
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Genomics DNA Profiling in Elite Professional Soccer Players: A Pilot Study
Translational medicine @ UniSa, 2014Functional variants in exonic regions have been associated with development of cardiovascular disease, diabetes and cancer. Athletic performance can be considered a multi-factorial complex phenotype.
M. Kambouris, A. Buono, Nicola Maffulli
semanticscholar +1 more source
DNA Methylation Profiling in Zebrafish [PDF]
, 2011 DNA methylation on cytosine in vertebrates such as zebrafish serves to silence gene expression by interfering with the binding of certain transcription factors and through the recruitment of repressive chromatin machinery. Cytosine DNA methylation is chemically stable and heritable through the germline - but also reversible through many modes, making ...
Shan-Fu Wu +10 more
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Plasma DNA end motif profiling as a fragmentomic marker in cancer, pregnancy and transplantation.
Cancer Discovery, 2020Plasma DNA fragmentomics is an emerging area of research covering plasma DNA sizes, end-points, and nucleosome footprints. In the present study, we found a significant increase in the diversity of plasma DNA end motifs in patients with hepatocellular ...
P. Jiang +20 more
semanticscholar +1 more source
DNA microarrays: raising the profile
Current Opinion in Biotechnology, 2001Expression profiling using DNA microarrays is starting to come of age. The past year has seen significant advances in the number, scope and quality of studies that incorporate expression profiling experiments. Attention is starting to move on from making DNA microarrays to appropriate experimental design and sophisticated data analysis techniques.
Frank C. P. Holstege +1 more
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DNA microarrays for expression profiling
Current Opinion in Chemical Biology, 2001DNA microarrays enable the transcript levels of an entire genome to be measured simultaneously. Recent improvements in array manufacture, sample preparation, and data analysis are shifting emphasis from the technology itself to experimental design and the broader range of biological questions that can be addressed.
Daniel D. Shoemaker, Timothy P. Hughes
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Degradation of forensic DNA profiles
Australian Journal of Forensic Sciences, 2013Selected profiles typed at the Promega PowerPlex 21 (PP21) loci were examined to determine if a linear or exponential model best described the relationship between peak height and molecular weight. There were fewer large departures from observed and expected peak heights using the exponential model.
Bright, Jo-Anne +3 more
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Checking of individuality by DNA profiling
Journal of Chromatography B: Biomedical Sciences and Applications, 1993A review of methods of DNA analysis used in forensic medicine for identification, paternity testing, etc. is provided. Among other techniques, DNA fingerprinting using different probes and polymerase chain reaction-based techniques such as amplified sequence polymorphisms and minisatellite variant repeat mapping are thoroughly described and both ...
R. Brdic̆ka, P. Nürnberg
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