Results 41 to 50 of about 5,488,409 (376)
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics, 2021 This article describes the application of the concept of geographic profiling in hunting a serial child rapist in Kasur, Pakistan. It also discusses, how DNA became the prime witness against the serial rapist in the court of law.
Muhammad Ahsan Butt +7 more
doaj +1 more source
STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods [PDF]
, 2017 The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis.
Cornelis, Senne +5 more
core +2 more sources
The utility of NBS profiling for plant systematics: a first study in tuber-bearing Solanum species [PDF]
, 2008 Systematic relationships are important criteria for researchers and breeders to select materials. We evaluated a novel molecular technique, nucleotide binding site (NBS) profiling, for its potential in phylogeny reconstruction.
Berg, R.G., van den +3 more
core +2 more sources
Chemical profiling of DNA G-quadruplex-interacting proteins in live cells
Nature Chemistry, 2021 DNA–protein interactions regulate critical biological processes. Identifying proteins that bind to specific, functional genomic loci is essential to understand the underlying regulatory mechanisms on a molecular level.
Xiaoyun Zhang +4 more
semanticscholar +1 more source
The effect of mark enhancement techniques on the presumptive and confirmatory tests for blood [PDF]
, 2018 An investigation into the effects of physical and chemical enhancement on subsequent presumptive and confirmatory tests for human blood is presented. Human blood was deposited onto porous (white 80gsm paper and brown envelope) and non-porous (tile and ...
Deacon, Paul +4 more
core +4 more sources
Neuro-Oncology, 2021 BACKGROUND Genome-wide DNA methylation profiling has recently been developed into a tool that allows tumor classification in central nervous system tumors.
C. Maire +25 more
semanticscholar +1 more source
DNA Polymerase Profiling [PDF]
, 2008 We report a simple homogeneous fluorescence assay for quantification of DNA polymerase function in high throughput. The fluorescence signal is generated by the DNA polymerase triggering opening of a molecular beacon extension of the template strand. A resulting distance alteration is reported by fluorescence resonance energy transfer between two dyes ...
openaire +3 more sources
DNA Methylation Profiling in Rare Sellar Tumors
Biomedicines, 2022 The histologic diagnosis of sellar masses can be challenging, particularly in rare neoplasms and tumors without definitive biomarkers. Moreover, there is significant inter-observer variability in the histopathological diagnosis of many tumors of the CNS,
Kyla Wright +3 more
doaj +1 more source
Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity. [PDF]
, 2018 Here we introduce Protein-indexed Assay of Transposase Accessible Chromatin with sequencing (Pi-ATAC) that combines single-cell chromatin and proteomic profiling. In conjunction with DNA transposition, the levels of multiple cell surface or intracellular
Chang, Howard Y +8 more
core +2 more sources
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH
bioRxiv, 2021 CRISPR-CATCH is used to isolate extrachromosomal DNA (ecDNA) molecules containing oncogenes from human cancer cells. CRISPR-CATCH followed by nanopore sequencing allows for methylation profiling, highlighting differences from the native chromosomal loci.
King L. Hung +8 more
semanticscholar +1 more source