Results 191 to 200 of about 1,028,456 (338)

Conserved 3D genome reorganization during DNA repair. [PDF]

Life Sci Alliance
Kaya VO, Adebali O, Naegeli H, Yancoskie MN.   +3 more
europepmc   +1 more source

XLF extends its range from DNA repair to replication [PDF]

, 2019
Yanira Gonzalez-Rodriguez, Samuel F. Bunting   +1 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

DNA DAMAGE-REPAIR IN BRAIN HEALTH AND DISEASE: FROM MECHANISMS TO INNOVATIVE THERAPIES

IBRO Neuroscience Reports, 2023
Muralidhar Hegde
doaj   +1 more source

Visualizing DNA repair factor recruitment at sites of transcription in single cells. [PDF]

Chromosome Res
Guan T, Shi Y, Lee TH, Oberdoerffer P.
europepmc   +1 more source

DNA Repair [PDF]

Journal of Thoracic Oncology, 2009
Ujhazy, Peter, Stewart, David
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

RA-risk synovium exhibits DNA damage coupled with impaired DNA repair in fibroblasts. [PDF]

RMD Open
O'Byrne AM, de Jong TA, Semmelink JF, Krawczyk PM, Hoebe RA, van de Sande M, van Baarsen L.   +6 more
europepmc   +1 more source

The Role of DNA Repair in Maintaining Mitochondrial DNA Stability

, 2017
Linlin Zhang, Aurelio Reyes, Xiangdong Wang   +2 more
openalex   +1 more source

Polymorphism of the DNA repair genes RAD51 and XRCC2 in smoking- and drinking-related laryngeal cancer in a Polish population [PDF]

, 2012
Hanna Romanowicz‐Makowska, Beata Smolarz, Marzena Gajęcka, Katarzyna Kiwerska, Małgorzata Rydzanicz, Dariusz Kaczmarczyk, Jurek Olszewski, Krzysztof Szyfter, Janusz Błasiak, Alina Morawiec-Sztandera   +9 more
openalex   +1 more source