Results 191 to 200 of about 3,431,424 (346)

Mechanisms for initiating cellular DNA replication

Science, 2017
F. Bleichert, M. Botchan, J. Berger
semanticscholar   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

A Bacteriophage-Derived Primase-Helicase Orchestrates Plant Organellar DNA Replication. [PDF]

Physiol Plant
Morales-Vázquez CM, Dagio-Hernandez MA, Camacho-Manriquez LD, Peralta-Castro A, Raygoza CD, Solano-Argüello D, Mora-Garduño JD, Gonzalez-Gonzalez R, Herrera-Ubaldo H, Díaz-Quezada C, Cruz-Ramírez A, de Folter S, Pedroza-García JA, Brieba LG.   +13 more
europepmc   +1 more source

Gene D5 product of bacteriophage T5: DNA-binding protein affecting DNA replication and late gene expression [PDF]

, 1979
D. James McCorquodale, J Gossling, Rolf Benzinger, Robert H. Chesney, Larry Lawhorne, Richard W. Moyer   +5 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

DNA replication initiation timing is important for maintaining genome integrity. [PDF]

J Bacteriol
Reed TT, Kendal AH, Wozniak KJ, Simmons LA.   +3 more
europepmc   +1 more source

Replication process of the parvovirus H-1. VI. Characterization of a replication terminus of H-1 replicative-form DNA [PDF]

, 1977
S L Rhode
openalex   +1 more source

Targeting replication stress in cancer therapy

Nature reviews. Drug discovery, 2022
A. D. da Costa, Dipanjan Chowdhury, G. Shapiro, A. D’Andrea, P. Konstantinopoulos   +4 more
semanticscholar   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Identification of Cdc45-interacting partners uncovers two Leishmania donovani proteins involved in DNA replication. [PDF]

BMC Microbiol
Dashora V, Singh A, Pandey A, Saha S.
europepmc   +1 more source