Results 201 to 210 of about 3,738,521 (387)

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

THE NEGATIVE CONTROL MECHANISM FOR E. coli DNA REPLICATION [PDF]

, 1969
Barbara Hatch Rosenberg, Liebe F. Cavalieri, Grace E. Ungers   +2 more
openalex   +1 more source

DNA replication.

Journal of Biological Chemistry, 1984
openaire   +3 more sources

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Mechanisms and regulation of DNA replication initiation in eukaryotes

Critical reviews in biochemistry and molecular biology, 2017
M. Parker, M. Botchan, J. Berger
semanticscholar   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

HOST SPECIFICITY OF DNA PRODUCED BY Escherichia coli , XI. In vitro MODIFICATION OF PHAGE FD REPLICATIVE FORM

, 1969
U. Kühnlein, Stuart Linn, Werner Arber
openalex   +2 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

THE MOLECULAR SYNCHRONY AND SEQUENTIAL REPLICATION OF DNA IN ESCHERICHIA COLI [PDF]

, 1963
Toshio Nagata
openalex   +1 more source

Mechanisms of DNA replication termination

Nature reviews. Molecular cell biology, 2017
James M. Dewar, J. Walter
semanticscholar   +1 more source