The role of DNA restriction-modification systems in the biology of Bacillus anthracis
Frontiers in Microbiology, 2016 Restriction-modification (R-M) systems are widespread among prokaryotes and, depending on their type, may be viewed as selfish genetic elements that persist as toxin-antitoxin modules or as cellular defense systems against phage infection.
Ramakrishnan eSitaraman
doaj +1 more source
The development of techniques to distinguish species and strains of giardia : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]
, 1995 Water supplies, in some rural areas of New Zealand, contain Giardia cysts. This is assumed to make the water unsuitable for human consumption. G. intestinalis and/or G. muris cysts may be present but are not distinguished by the standard test. G.
Farrant, Kirsty Jane
core
A species-specific satellite DNA family in the genome of the coffee root-knot nematode Meloidogyne exigua : Application to molecular diagnostics of the parasite [PDF]
, 2002 A new Bg/II satellite DNA has been isolated, cloned and sequenced from the coffee root-knot nematode, Meloidogyne exigua (Nematoda: Tylenchida). It is represented as tandemly repeated sequences with a monomeric unit of 277 bp. The monomers are present at
Bongiovanni, Michel +4 more
core +2 more sources
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Restriction enzyme analysis of the chloroplast DNA of Phaseolus vulgaris L. vr. Rio Negro [PDF]
, 1996 Sérgio Echeverrigaray +2 more
openalex +1 more source
A Small Family of Elements with Long Inverted Repeats is Located Near Sites of Developmentally Regulated DNA Rearrangement in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]
, 1994 Extensive DNA rearrangement occurs during the development of the somatic macronucleus from the germ line micronucleus in ciliated protozoans. The micronuclear junctions and the macronuclear product of a developmentally regulated DNA rearrangement in ...
Berger, Patricia J. +4 more
core +1 more source
, 2010 We propose a novel theoretical biomolecular design to implement any Boolean circuit using the mechanism of DNA strand displacement. The design is scalable: all species of DNA strands can in principle be mixed and prepared in a single test tube, rather ...
A. Goel +8 more
core +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Mechanism of DNA Recognition by the Restriction Enzyme EcoRV
Journal of Molecular Biology, 2010 EcoRV, a restriction enzyme in Escherichia coli, destroys invading foreign DNA by cleaving it at the center step of a GATATC sequence. In the EcoRV-cognate DNA crystallographic complex, a sharp kink of 50 degrees has been found at the center base-pair step (TA).
Zahran M +3 more
openaire +4 more sources
Simple enzymatic means to neutralize DNA contamination in nucleic acid amplification
BioTechniques, 2005 Reverse transcription PCR (RT-PCR) is prone to false positives when contaminating DNA molecules are present at the start of a reaction. Contaminants that derive from earlier work using a given primer pair (carryover PCR products) are of particular ...
John Ashkenas +2 more
doaj +1 more source