Results 111 to 120 of about 390,387 (330)

Isolasi karakterisasi dan uji ekspresi gen ALP1 SI Escherichia coli DH5a

Journal of Biological Researches, 1999
Amylase gene (ALP1) insertion in YCp 50 cloning vector was detected by Direct Screening PCR. Result of Direct Screening PCR showed one transformants which assumed have amylase gene insert.
Ni Nyoman Tri Puspaningsih, Akhmaloka Akhmaloka, Sofyan Hadi, Y. Sriwulan Manuhara, Bambang Irawan   +4 more
doaj   +1 more source

Cytosine-to-Uracil Deamination by SssI DNA Methyltransferase [PDF]

, 2013
The prokaryotic DNA(cytosine-5)methyltransferase M.SssI shares the specificity of eukaryotic DNA methyltransferases (CG) and is an important model and experimental tool in the study of eukaryotic DNA methylation.
A Beletskii, A Jeltsch, AN Sharath, Antal Kiss, AS Yang, B Bandaru, B Bandaru, B Chaikind, BM Hall, BTF van der Gun, DM Woodcock, EA Raleigh, EU Selker, EV Koudan, G Pósfai, GL Xu, H Gowher, I Stier, Ildikó Stier, J Sambrook, JC Shen, JC Shen, JC Shen, JM Zingg, JM Zingg, KM Reinisch, LA Frederico, LM Guzman, M Frommer, M Wyszynski, Martin G. Marinus, MH Sibley, P Rathert, P Renbaum, PA Waite-Rees, PM Warnecke, R Métivier, R Shapiro, RJ Roberts, RY-H Wang, S Kumar, SE Luria, T Durfee, TA Kunkel, UT Sankpal, WA Rosche, X Cheng, X Zhang   +47 more
core   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

The role of DNA restriction-modification systems in the biology of Bacillus anthracis

Frontiers in Microbiology, 2016
Restriction-modification (R-M) systems are widespread among prokaryotes and, depending on their type, may be viewed as selfish genetic elements that persist as toxin-antitoxin modules or as cellular defense systems against phage infection.
Ramakrishnan eSitaraman
doaj   +1 more source

Relationship between spawning mode and phylogeographic structure in mitochondrial DNA of North Atlantic capelin Mallotus villosus [PDF]

, 1991
Capelin Mallotus villosus spawn on beaches in Alaska and British Columbia, but spawn offshore in Icelandic waters and the Barents Sea. Both modes of reproduction CO-occur In the northwest Atlantic. The Southeast Shoal population spawns on the Grand Banks
Bernatchez, Louis, Carscadden, J.E., Colombani, Franqoise, Dodson, Julian J.   +3 more
core  

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Computer Aided Simulation of DNA Fingerprint Amplified Fragment Length Polymophism (AFLP) Using Suffix Tree Indexing and Data Mining [PDF]

, 2011
AFLP is one of the DNA Fingerprinting techniques which have broad application as genetic marker in various fields. Begin with the DNA sequence digestion using one or more particular restriction enzyme, ligation of the adapters to the overhanging sticky ...
Budiman, Agung, Prilianti, Kestrilia Rega, Putra, Sulistyo Emantoko Dwi, Whendy, Bhinawan   +3 more
core  

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples

Nature Communications, 2019
Genomics DNA library preparation from formalin-fixed paraffin-embedded tissues is challenging. Here the authors describe CUTseq that uses restriction enzymes and in vitro amplification to barcode samples for reduced representation genome sequencing.
Xiaolu Zhang, Silvano Garnerone, Michele Simonetti, Luuk Harbers, Marcin Nicoś, Reza Mirzazadeh, Tiziana Venesio, Anna Sapino, Johan Hartman, Caterina Marchiò, Magda Bienko, Nicola Crosetto   +11 more
doaj   +1 more source

A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes [PDF]

, 2017
A nomenclature is described for restriction endonucleases, DNA methyltransferases, homing endonucleases and related genes and gene products. It provides explicit categories for the many different Type II enzymes now identified and provides a system for ...
Belfort, Marlene, Bestor, Timothy, Bhagwat, Ashok S., Bickle, Thomas A., Bitinaite, Jurate, Blumenthal, Robert M., Degtyarev, Sergey Kh, Dryden, David T. F., Dybvig, Kevin, Firman, Keith, Gromova, Elizaveta S., Gumport, Richard I., Halford, Stephen E., Hattman, Stanley, Heitman, Joseph, Hornby, David P., Janulaitis, Arvydas, Jeltsch, Albert, Josephsen, Jytte, Kiss, Antal, Klaenhammer, Todd R., Kobayashi, Ichizo, Kong, Huimin, Krüger, Detlev H., Lacks, Sanford, Marinus, Martin G., Miyahara, Michiko, Morgan, Richard D., Murray, Noreen E., Nagaraja, Valakunja, Piekarowicz, Andrzej, Pingoud, Alfred, Raleigh, Elisabeth, Rao, Desirazu N., Reich, Norbert, Repin, Vladimir E., Roberts, Richard J., Selker, Eric U., Shaw, Pang‐Chui, Stein, Daniel C., Stoddard, Barry L., Szybalski, Waclaw, Trautner, Thomas A., Van Etten, James L., Vitor, Jorge M. B., Wilson, Geoffrey G., Xu, Shuang‐yong   +46 more
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