Results 161 to 170 of about 391,854 (357)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes [PDF]

, 2017
A nomenclature is described for restriction endonucleases, DNA methyltransferases, homing endonucleases and related genes and gene products. It provides explicit categories for the many different Type II enzymes now identified and provides a system for ...
Belfort, Marlene, Bestor, Timothy, Bhagwat, Ashok S., Bickle, Thomas A., Bitinaite, Jurate, Blumenthal, Robert M., Degtyarev, Sergey Kh, Dryden, David T. F., Dybvig, Kevin, Firman, Keith, Gromova, Elizaveta S., Gumport, Richard I., Halford, Stephen E., Hattman, Stanley, Heitman, Joseph, Hornby, David P., Janulaitis, Arvydas, Jeltsch, Albert, Josephsen, Jytte, Kiss, Antal, Klaenhammer, Todd R., Kobayashi, Ichizo, Kong, Huimin, Krüger, Detlev H., Lacks, Sanford, Marinus, Martin G., Miyahara, Michiko, Morgan, Richard D., Murray, Noreen E., Nagaraja, Valakunja, Piekarowicz, Andrzej, Pingoud, Alfred, Raleigh, Elisabeth, Rao, Desirazu N., Reich, Norbert, Repin, Vladimir E., Roberts, Richard J., Selker, Eric U., Shaw, Pang‐Chui, Stein, Daniel C., Stoddard, Barry L., Szybalski, Waclaw, Trautner, Thomas A., Van Etten, James L., Vitor, Jorge M. B., Wilson, Geoffrey G., Xu, Shuang‐yong   +46 more
core  

Tagging developmental genes in Dictyostelium by restriction enzyme-mediated integration of plasmid DNA. [PDF]

, 1992
Adam Kuspa, William F. Loomis
openalex   +1 more source

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

Molecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová, Hana Svozilová, Marcela Krzyžánková, Radim Sonnek, Anastasiya Volakhava, Anastasia Smirnova, Tatiana Grigoreva, Zuzana Jašková, Hana Synáčková, Dennis Wahl, Michaela Bilčíková, Libor Červinek, Šárka Pospíšilová, Ilgar Mamedov, Karla Plevová   +14 more
wiley   +1 more source

Polymerase-endonuclease amplification reaction for large-scale enzymatic production of antisense oligonucleotide [PDF]

, 2009
Synthetic oligonucleotides are contaminated with highly homologous failure sequences. Oligonucleotide synthesis is difficult to scale up because it requires expensive equipments, hazardous chemicals, and tedious purification process.
Deming Gou, Xiaolong Wang
core   +1 more source

PCR-Restriction Enzyme Analysis for Detection of Candida DNA in Blood from Febrile Patients with Hematological Malignancies [PDF]

, 1999
Giulia Morace, Livio Pagano, Maurizio Sanguinetti, Brunella Posteraro, Luca Mele, Francesco Equitani, Giuseppina D’Amore, Giuseppe Leone, Giovanni Fadda   +8 more
openalex   +1 more source

The tumor–microbe connection

Molecular Oncology, EarlyView.
Tumor‐associated bacteria (TAB) dynamically influence cancer biology by modulating tumor progression, metastatic spread, and therapeutic efficacy. Their presence redefines the tumor microenvironment (TME) as a microbial–host interface, yet mechanistic insights remain limited. Understanding TAB colonization routes, functional impacts, and crosstalk with
Gerlanda Vella, Maria Rescigno
wiley   +1 more source

Nonhomologous End Joining during Restriction Enzyme-Mediated DNA Integration in Saccharomyces cerevisiae [PDF]

, 1998
P. Manivasakam, Robert H. Schiestl
openalex   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Restriction enzyme analysis of mouse cellular type C viral DNA: emergence of new viral sequences in spontaneous AKR/J lymphomas.

, 1979
Eli Canaani, Stuart A. Aaronson
openalex   +1 more source