Results 251 to 260 of about 405,469 (354)

Effect of deoxynucleoside phosphorothioates incorporated in DNA on cleavage by restriction enzymes.

, 1982
Hans-Peter Vosberg, F. Eckstein
openalex   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Mercury exposure, epigenetic modifications, and genetic susceptibility: insights from molecular docking and population analysis. [PDF]

Front Public Health
Serik B, Shinetova LE, Efimova NV, Bekeyeva SA, Abdrakhmanova BM, Dauletova AO, Suleimenova RK, Mussin NM, Zare A, Safarzoda Sharoffidin R, Tamadon A.   +10 more
europepmc   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

Amino acids metabolism: a potential target for cancer treatment. [PDF]

Mol Cancer
Ren S, Zhou X, Wang Z, Yuan K.
europepmc   +1 more source

Molecular Cloning and Expression of a Novel Hydroxymethylcytosine-specific Restriction Enzyme (PvuRts1I) Modulated by Glucosylation of DNA

, 1994
László Jánosi, Hiroishi Yonemitsu, Howard Hong, Akira Kaji   +3 more
openalex   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution. [PDF]

Nucleic Acids Res
Loedige KW, Hall MA, Ghimirey S, Stead BE, Edgell DR.   +4 more
europepmc   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Generation of high-quality single-stranded DNA for full-length and truncated genome standards of recombinant adeno-associated viruses. [PDF]

Mol Ther Methods Clin Dev
Manz J, Ruppert R, Haindl M, Hubbuch J, Graf T, Pschirer J.   +5 more
europepmc   +1 more source