Results 171 to 180 of about 3,767,606 (374)

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

Proceedings of the National Academy of Sciences of the United States of America, 1987
S. Tabor, C. Richardson
semanticscholar   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies

Haematologica, 2015
Xinan Wang, Hideki Muramatsu, Yusuke Okuno, Hirotoshi Sakaguchi, Kenichi Yoshida, Nozomu Kawashima, Yinyan Xu, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Shoji Saito, Yozo Nakazawa, Taro Masunari, Tadashi Hirose, Shaimaa Elmahdi, Atsushi Narita, Sayoko Doisaki, Olfat Ismael, Hideki Makishima, Asahito Hama, Satoru Miyano, Yoshiyuki Takahashi, Seishi Ogawa, Seiji Kojima   +23 more
doaj   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Nucleotide sequence of a fragment of SV40 DNA that contains the origin of DNA replication and specifies the 5' ends of "early" and "late" viral RNA. I. Mapping of the restriction endonuclease sites within the EcoRII-G fragment and strategy employed for its sequence analysis.

, 1977
K. N. Subramanian, Ravi Dhar, S Weissman
openalex   +1 more source

Tandem direct duplications of mitochondrial DNA in mitochondrial myopathy: analysis of nucleotide sequence and tissue distribution [PDF]

, 1989
Joanna Poulton, Mary E. Deadman, R M Gardiner   +2 more
openalex   +1 more source

Light-generated oligonucleotide arrays for rapid DNA sequence analysis.

Proceedings of the National Academy of Sciences of the United States of America, 1994
A. C. Pease, D. Solas, E. Sullivan, M. Cronin, C. Holmes, S. P. Fodor   +5 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Sequence analysis of two yeast mitochondrial DNA fragments containing the genes for tRNA Ser UCR and tRNA Phe UUY.

, 1979
Dennis L. Miller, Nicola Martin, H.D. Pham, J E Donelson   +3 more
openalex   +1 more source

Molecular analysis of the DNA sequences involved in the transcriptional regulation of the phosphate-repressible acid phosphatase gene (PHO5) of Saccharomyces cerevisiae. [PDF]

, 1986
Lawrence W. Bergman, Diana Mcclinton, Stephen F. Madden, L. H. Preis   +3 more
openalex   +1 more source