Results 11 to 20 of about 3,677,492 (346)
Applications of Single-Cell DNA Sequencing.
Annual review of genomics and human genetics (Print), 2021 Over the past decade, genomic analyses of single cells-the fundamental units of life-have become possible. Single-cell DNA sequencing has shed light on biological questions that were previously inaccessible across diverse fields of research, including ...
Gilad D. Evrony, A. Hinch, C. Luo
semanticscholar +1 more source
Infectious Diseases and Therapy, 2023 Introduction The introduction of pneumococcal conjugate vaccines (PCV) into the national immunization programs (NIPs) has significantly reduced the number of pneumococcal infections.
Weronika Puzia +9 more
doaj +1 more source
Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA
Genome Research, 2021 Bisulfite sequencing detects 5mC and 5hmC at single-base resolution. However, bisulfite treatment damages DNA, which results in fragmentation, DNA loss, and biased sequencing data.
Romualdas Vaisvila +19 more
semanticscholar +1 more source
BARCOSEL: a tool for selecting an optimal barcode set for high-throughput sequencing
BMC Bioinformatics, 2018 Background Current high-throughput sequencing platforms provide capacity to sequence multiple samples in parallel. Different samples are labeled by attaching a short sample specific nucleotide sequence, barcode, to each DNA molecule prior pooling them ...
Panu Somervuo +5 more
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An in vivo patient-derived model of endogenous IDH1-mutant glioma.
Neuro-Oncology, 2012 Somatic mutations in the catalytic domain of isocitrate dehydrogenase (IDH) 1/2 and accumulation of the oncometabolite 2-hydroxyglutarate (2-HG) appear to be among the earliest events in gliomagenesis and may contribute to malignant transformation.
H. A. Luchman +14 more
semanticscholar +1 more source
Case Report of COVID-19 after Full Vaccination: Viral Loads and Anti-SARS-CoV-2 Antibodies
Diagnostics, 2021 The introduction of effective vaccines against SARS-CoV-2 is expected to prevent COVID-19. However, sporadic cases of infection in vaccinated persons have been reported. We describe a case of a double-dose vaccinated woman with COVID-19.
Magdalena Komiazyk +5 more
doaj +1 more source
Genome Research, 2010 Next-generation DNA sequencing (NGS) projects, such as the 1000 Genomes Project, are already revolutionizing our understanding of genetic variation among individuals.
A. McKenna +10 more
semanticscholar +1 more source
The sequence of sequencers: The history of sequencing DNA
Genomics, 2016 Determining the order of nucleic acid residues in biological samples is an integral component of a wide variety of research applications. Over the last fifty years large numbers of researchers have applied themselves to the production of techniques and technologies to facilitate this feat, sequencing DNA and RNA molecules. This time-scale has witnessed
Heather, JM, Chain, B
openaire +4 more sources
A framework for variation discovery and genotyping using next-generation DNA sequencing data
Nature Genetics, 2011 Recent advances in sequencing technology make it possible to comprehensively catalog genetic variation in population samples, creating a foundation for understanding human disease, ancestry and evolution.
M. DePristo +17 more
semanticscholar +1 more source
Nature Biotechnology, 2021 Circulating tumor-derived DNA (ctDNA) is an emerging biomarker for many cancers, but the limited sensitivity of current detection methods reduces its utility for diagnosing minimal residual disease.
D. Kurtz +28 more
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