Results 11 to 20 of about 1,188,878 (324)

The sequence of sequencers: The history of sequencing DNA

open access: yesGenomics, 2016
Determining the order of nucleic acid residues in biological samples is an integral component of a wide variety of research applications. Over the last fifty years large numbers of researchers have applied themselves to the production of techniques and technologies to facilitate this feat, sequencing DNA and RNA molecules. This time-scale has witnessed
Heather, JM, Chain, B
openaire   +4 more sources

A first insight into the genome of Prototheca wickerhamii, a major causative agent of human protothecosis

open access: yesBMC Genomics, 2021
Background Colourless microalgae of the Prototheca genus are the only known plants that have consistently been implicated in a range of clinically relevant opportunistic infections in both animals and humans.
Zofia Bakuła   +7 more
doaj   +1 more source

Exoquence DNA sequencing [PDF]

open access: yesNucleic Acids Research, 1993
We have developed a strategy for DNA sequencing based on exonuclease III digestion followed by double strand specific endonuclease digestion and direct dideoxynucleotide sequencing reaction. This strategy eliminates the need for subcloning, oligonucleotide primers, and prior knowledge of the DNA to be sequenced.
Chuan Li, Philip W. Tucker
openaire   +3 more sources

An optimized method for high quality DNA extraction from microalga Prototheca wickerhamii for genome sequencing

open access: yesPlant Methods, 2017
Background The complex cell wall structure of algae often precludes efficient extraction of their genetic material. The purpose of this study was to design a next-generation sequencing-suitable DNA isolation method for unicellular, achlorophyllous, yeast-
Tomasz Jagielski   +5 more
doaj   +1 more source

Bacterial Communities Associated with Poa annua Roots in Central European (Poland) and Antarctic Settings (King George Island)

open access: yesMicroorganisms, 2021
Poa annua (annual bluegrass) is one of the most ubiquitous grass species in the world. In isolated regions of maritime Antarctica, it has become an invasive organism threatening native tundra communities.
Anna Znój   +4 more
doaj   +1 more source

Genome description of Phlebia radiata 79 with comparative genomics analysis on lignocellulose decomposition machinery of phlebioid fungi

open access: yesBMC Genomics, 2019
Background The white rot fungus Phlebia radiata, a type species of the genus Phlebia, is an efficient decomposer of plant cell wall polysaccharides, modifier of softwood and hardwood lignin, and is able to produce ethanol from various waste ...
Mari Mäkinen   +9 more
doaj   +1 more source

Divergent northern and southern populations and demographic history of the pearl oyster in the western Pacific revealed with genomic SNPs

open access: yesEvolutionary Applications, 2020
In the open ocean without terrain boundaries, marine invertebrates with pelagic larvae can migrate long distances using ocean currents, suggesting reduced genetic diversification.
Takeshi Takeuchi   +5 more
doaj   +1 more source

DNA Sequences at a Glance

open access: yesPLoS ONE, 2013
Data summarization and triage is one of the current top challenges in visual analytics. The goal is to let users visually inspect large data sets and examine or request data with particular characteristics. The need for summarization and visual analytics is also felt when dealing with digital representations of DNA sequences.
Armando J. Pinho   +3 more
openaire   +5 more sources

Comparative genomics of four strains of the edible brown alga, Cladosiphon okamuranus

open access: yesBMC Genomics, 2020
Background The brown alga, Cladosiphon okamuranus (Okinawa mozuku), is one of the most important edible seaweeds, and it is cultivated for market primarily in Okinawa, Japan.
Koki Nishitsuji   +7 more
doaj   +1 more source

Fast DNA sequencing

open access: yesMedical Hypotheses, 2000
A method for fast nucleotide sequencing is described. It is based in the selection of well-known small oligomers able to be hybridized with the unknown target. The selected oligomers are afterwards ordered following a simple statistical approach. The use of capillary electrophoresis for the analysis is emphasized.
Figureau, A., Soto, M.A., Toha, J.
openaire   +6 more sources

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