Results 201 to 210 of about 1,741,840 (332)

An improved method for sequencing double stranded plasmid DNA from minipreps using DMSO and modified template preparation [PDF]

, 1990
Donald Seto
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Precise measurement of CRISPR genome editing outcomes through single-cell DNA sequencing. [PDF]

Mol Ther Methods Clin Dev
Kalter N, Gulati S, Rosenberg M, Ayaz Q, Nguyen J, Wang S, Schroeder B, Li CY, Hendel A.   +8 more
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Identification of Novel Hb Guiyang [HBA2: c.151C > A α2 50 (CE8) His- Asn] and Phenotype- Genotype Correlation of Abnormal Hemoglobins in Guizhou, Southwest China

Journal of Blood Medicine
Ya-Ping Chen,1,2 Heng Wang,1,3 Lei Wang,4 Dan Xie,4 Min Guo,4 Jiang-Fen Wu,5 Bang-Quan An,6 Sheng-Wen Huang1,5 1School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, Guizhou, People’s Republic of China; 2Department of Clinical ...
Chen YP, Wang H, Wang L, Xie D, Guo M, Wu JF, An BQ, Huang SW   +7 more
doaj  

Culture-negative liver abscess identified with plasma microbial cell-free DNA sequencing: A case report. [PDF]

Infect Med (Beijing)
Xue Y, Cerqueira FM, Stevenson HL, Williams-Bouyer N, Fang R.   +4 more
europepmc   +1 more source

Isolation, sequencing and overexpression of the gene encoding theθsubunit of DNA polymerase III holoenzyme [PDF]

, 1993
Jefferey Carter, Mary Ann Franden, Ruedi Aebersold, Doek Ryong Kim, Charles S. McHenry   +4 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Plasma Microbial Cell-free DNA Sequencing for the Detection of Kingella kingae Pediatric Spinal Infections. [PDF]

Pediatr Infect Dis J
Ahmed AA, Park SY, Smollin MJ, Lindner MS, Sarmiento Clemente A, Del Valle Penella A, Laufer PM, Sanchez-Vegas C, Cotilla MR, Melish ME, Trieu C, Kabani NA, Cooper J, Lloyd AR, Kimberlin DW, Arnold JC, Jordan-Villegas A, Patterson LE, Foster CE, Yagupsky P.   +19 more
europepmc   +1 more source

Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme [PDF]

, 1992
J R Carter, Mary Ann Franden, Ruedi Aebersold, Charles S. McHenry   +3 more
openalex   +1 more source