Results 201 to 210 of about 1,188,878 (324)

Identification of Novel Hb Guiyang [HBA2: c.151C > A α2 50 (CE8) His- Asn] and Phenotype- Genotype Correlation of Abnormal Hemoglobins in Guizhou, Southwest China

Journal of Blood Medicine
Ya-Ping Chen,1,2 Heng Wang,1,3 Lei Wang,4 Dan Xie,4 Min Guo,4 Jiang-Fen Wu,5 Bang-Quan An,6 Sheng-Wen Huang1,5 1School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, Guizhou, People’s Republic of China; 2Department of Clinical ...
Chen YP, Wang H, Wang L, Xie D, Guo M, Wu JF, An BQ, Huang SW   +7 more
doaj  

A regression based approach to phylogenetic reconstruction from multi-sample bulk DNA sequencing of tumors. [PDF]

PLoS Comput Biol
Schmidt H, Raphael BJ.
europepmc   +1 more source

Heterogeneity in lung cancers by single-cell DNA sequencing. [PDF]

Clin Transl Med, 2023
Zhang L, Chen L, Li SC, Wang M, Li C, Song T, Ni Y, Yang Y, Liu Z, Yao M, Shen B, Li W.   +11 more
europepmc   +1 more source

pDUAL: a transposon-based cosmid cloning vector for generating nested deletions and DNA sequencing templates in vivo. [PDF]

, 1993
G Wang, Robert W. Blakesley, Douglas E. Berg, Christina Berg   +3 more
openalex   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme [PDF]

, 1992
J R Carter, Mary Ann Franden, Ruedi Aebersold, Charles S. McHenry   +3 more
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Whole Mitochondrial DNA Sequencing Using Fecal Samples from Domestic Dogs. [PDF]

Animals (Basel)
Sugasawa T, Nguyen KDM, Otani N, Maehara K, Kamiya F, Hirokawa A, Takemasa T, Watanabe K, Nishi T, Sato K, Shimmura S, Takahashi Y, Kanki Y.   +12 more
europepmc   +1 more source

Strategies for direct sequencing of PCR-amplified DNA. [PDF]

, 1994
Venigalla B. Rao
openalex   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source