Results 271 to 280 of about 1,871,571 (343)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Analysis of genomic heterogeneity and the mutational landscape in cutaneous squamous cell carcinoma through multi-patient-targeted single-cell DNA sequencing. [PDF]

BMC Cancer
Chen W, Xu J, Yu C, Zhou M, Ai Y, Rao W, Wang Q, Xu S, Tang L, Gong S, Rao J.   +10 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Global stock structure of the Silky shark (<i>Carcharhinus falciformis</i>, Carcharhinidae) assessed with high-throughput DNA sequencing. [PDF]

PeerJ
Kraft DW, Conklin EE, Freel EB, Hutchinson M, Spaet JLY, Toonen RJ, Forsman ZH, Grant MI, Filmalter JD, Hyde JR, Gulak SJB, Bowen BW.   +11 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

A Delphi study on valuing DNA sequencing in oncology: a European stakeholder developed framework for assessing next generation sequencing and comprehensive genomic profiling diagnostics. [PDF]

EBioMedicine
Federico A, Danitza C, Madeleine H, Caitlin M, Fernando A, Carla C, Mackenzie M, Verónica A, Andrés PR, Andrea A, Panos K.   +10 more
europepmc   +1 more source

Precise measurement of CRISPR genome editing outcomes through single-cell DNA sequencing. [PDF]

Mol Ther Methods Clin Dev
Kalter N, Gulati S, Rosenberg M, Ayaz Q, Nguyen J, Wang S, Schroeder B, Li CY, Hendel A.   +8 more
europepmc   +1 more source

Absolute copy number aware CNV calling of sub-megabase segments in ultra-low coverage single-cell DNA sequencing data. [PDF]

Nucleic Acids Res
Kolbeinsdottir S, Zachariadis V, Sommerauer C, Lohi O, Heinäniemi M, Enge M.   +5 more
europepmc   +1 more source