Results 271 to 280 of about 1,359,741 (317)
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Science, 1988
The increasing demand for DNA sequences can be met by replacement of each DNA sample in a device with a mixture of N samples so that the normal throughput is increased by a factor of N . Such a method is described.
G M, Church, S, Kieffer-Higgins
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The increasing demand for DNA sequences can be met by replacement of each DNA sample in a device with a mixture of N samples so that the normal throughput is increased by a factor of N . Such a method is described.
G M, Church, S, Kieffer-Higgins
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Science, 1993
This article describes the emerging technologies for rapid sequencing of DNA. Technologies discussed include the use of ultrathin gels, replaceable or reusable gels, automated systems, new types of primers to replace the current shotgun method of DNA sequencing, mass spectrometric direct sequencing technologies, and sequencing by hybridization.
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This article describes the emerging technologies for rapid sequencing of DNA. Technologies discussed include the use of ultrathin gels, replaceable or reusable gels, automated systems, new types of primers to replace the current shotgun method of DNA sequencing, mass spectrometric direct sequencing technologies, and sequencing by hybridization.
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Proceedings of the Paris C. Kanellakis memorial workshop on Principles of computing & knowledge: Paris C. Kanellakis memorial workshop on the occasion of his 50th birthday, 2003
Paired-read shotgun sequencing of a genome consists of randomly sampling segments of a fixed length, say 10,000 base pairs (10Kbp), and directly determining a "read" of 500 to 700bp at the two ends of each segment with an automated DNA sequencing instrument.
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Paired-read shotgun sequencing of a genome consists of randomly sampling segments of a fixed length, say 10,000 base pairs (10Kbp), and directly determining a "read" of 500 to 700bp at the two ends of each segment with an automated DNA sequencing instrument.
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2010
Fluorescent cycle sequencing of PCR products is a multistage process and several methodologies are available to perform each stage. This chapter will describe the more commonly utilised dye-terminator cycle sequencing approach using BigDye® terminator chemistry (Applied Biosystems) ready for analysis on a 3730 DNA genetic analyzer.
Yvonne, Wallis, Natalie, Morrell
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Fluorescent cycle sequencing of PCR products is a multistage process and several methodologies are available to perform each stage. This chapter will describe the more commonly utilised dye-terminator cycle sequencing approach using BigDye® terminator chemistry (Applied Biosystems) ready for analysis on a 3730 DNA genetic analyzer.
Yvonne, Wallis, Natalie, Morrell
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Nature Methods, 2021
Loop-seq is a high-throughput sequencing assay that measures DNA looping and can help explain how DNA bendability contributes to nucleosome organization.
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Loop-seq is a high-throughput sequencing assay that measures DNA looping and can help explain how DNA bendability contributes to nucleosome organization.
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Science, 1999
The News Focus article by Eliot Marshall titled “A high-stakes gamble on genome sequencing” (18 June, p. [1906][1]) states that the PE Biosystems model 3700 DNA sequencer was developed by industry. While PE Biosystems invested significant resources in their outstanding engineering work for the instrument, the original prototypes were developed by H ...
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The News Focus article by Eliot Marshall titled “A high-stakes gamble on genome sequencing” (18 June, p. [1906][1]) states that the PE Biosystems model 3700 DNA sequencer was developed by industry. While PE Biosystems invested significant resources in their outstanding engineering work for the instrument, the original prototypes were developed by H ...
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Analytical Biochemistry, 1988
A modification of Lin's systematic DNA sequencing strategy is described. A method based on the religation of compatible cohesive ends generated by Sau3AI and BamHI was developed. The original procedure has been simplified and the yield of transfectant has been greatly improved.
Y M, Lee, S C, Lee
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A modification of Lin's systematic DNA sequencing strategy is described. A method based on the religation of compatible cohesive ends generated by Sau3AI and BamHI was developed. The original procedure has been simplified and the yield of transfectant has been greatly improved.
Y M, Lee, S C, Lee
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On enumerating the DNA sequences
Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine, 2012DNA sequences are denoted mostly in raw text format, where 2-bit compressed representations are preferred either to gain space or perform some processing fast via computers intrinsic bitwise operations, e.g., search applications. Studies aiming to compress DNA sequences have deployed various encoding schemes such as Lempel--Ziv type factorizations ...
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[Proceedings] DCC `93: Data Compression Conference, 2002
The authors propose a lossless algorithm based on regularities, such as the presence of palindromes, in the DNA. The results obtained, although not satisfactory, are far beyond classical algorithms. >
Stéphane Grumbach, Fariza Tahi
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The authors propose a lossless algorithm based on regularities, such as the presence of palindromes, in the DNA. The results obtained, although not satisfactory, are far beyond classical algorithms. >
Stéphane Grumbach, Fariza Tahi
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DNA Sequence Analysis and Comparative Sequencing
Methods, 1998Abstract This article aims to give an introduction to comparative sequencing and analysis, containing a brief section on sequence production, but focusing on the computer-based ( in silico ) analysis of genomic sequence.
A M, Mallon, M, Strivens
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