Results 21 to 30 of about 1,188,878 (324)
Static Virus Spread Algorithm for DNA Sequence Design [PDF]
DNA is not only the genetic material of life, but also a favorable material for a new computing model. Various research works based on DNA computing have been carried out in recent years. DNA sequence design is the foundation of such research. The sequence quality directly affects the universality, robustness, and stability of DNA computing.
arxiv
Melting Transition of Directly-Linked Gold Nanoparticle DNA Assembly [PDF]
DNA melting and hybridization is a fundamental biological process as well as a crucial step in many modern biotechnology applications. DNA confined on surfaces exhibits different behavior from that in free solutions. The system of DNA-capped gold nanoparticles exhibits unique phase transitions and represents a new class of complex fluids.
arxiv +1 more source
Defects Can Increase the Melting Temperature of DNA-Nanoparticle Assemblies [PDF]
DNA-gold nanoparticle assemblies have shown promise as an alternative technology to DNA microarrays for DNA detection and RNA profiling. Understanding the effect of DNA sequences on the melting temperature of the system is central to developing reliable detection technology.
arxiv +1 more source
AbstractSequencing of human and other genomes has been at the center of interest in the biomedical field over the past several decades and is now leading toward an era of personalized medicine. During this time, DNA‐sequencing methods have evolved from the labor‐intensive slab gel electrophoresis, through automated multiCE systems using fluorophore ...
András Guttman, Barry L. Karger
openaire +3 more sources
With the aim of expediting drug target discovery and validation for respiratory diseases, we developed an optimized method for in situ somatic gene disruption in murine lung epithelial cells via AAV6-mediated CRISPR-Cas9 delivery.
Honglin Chen+13 more
doaj
Highly accurate long reads are crucial for realizing the potential of biodiversity genomics
Background Generating the most contiguous, accurate genome assemblies given available sequencing technologies is a long-standing challenge in genome science.
Scott Hotaling+4 more
doaj +1 more source
Bisulfite Sequencing of DNA [PDF]
AbstractExact positions of 5‐methylcytosine (m5C) on a single strand of DNA can be determined by bisulfite genomic sequencing (BGS). Treatment with bisulfite ion preferentially deaminates unmethylated cytosines, which are then converted to uracil upon desulfonation.
Russell P. Darst+4 more
openaire +3 more sources
Complete mitochondrial genome of the freshwater prawn Palaemon capensis (Crustacea: Palaemonidae)
The complete mitogenome of Palaemon capensis is presented here. The mitogenome is 15,925 bp in length and comprises 13 protein coding genes, 2 ribosomal subunit genes, 22 transfer RNAs, and a non-coding AT-rich region.
Louisa E. Wood+3 more
doaj +1 more source
After publication of Nakano et al. (2017) [1], the authors became aware of the fact that the new species-group name erected for the two specimens of a Japanese xenoturbellid species in the article is not available because Nakano et al.
Hiroaki Nakano+9 more
doaj +1 more source
Genbit Compress Tool(GBC): A Java-Based Tool to Compress DNA Sequences and Compute Compression Ratio(bits/base) of Genomes [PDF]
We present a Compression Tool, "GenBit Compress", for genetic sequences based on our new proposed "GenBit Compress Algorithm". Our Tool achieves the best compression ratios for Entire Genome (DNA sequences) . Significantly better compression results show that GenBit compress algorithm is the best among the remaining Genome compression algorithms for ...
arxiv +1 more source