Results 21 to 30 of about 1,195,007 (265)

Highly accurate long reads are crucial for realizing the potential of biodiversity genomics

BMC Genomics, 2023
Background Generating the most contiguous, accurate genome assemblies given available sequencing technologies is a long-standing challenge in genome science.
Scott Hotaling, Edward R. Wilcox, Jacqueline Heckenhauer, Russell J. Stewart, Paul B. Frandsen   +4 more
doaj   +1 more source

Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells

STAR Protocols, 2021
Summary: Genome-wide nuclear run-ons are a powerful way to determine the impact of a perturbation such as transcription factor degradation on transcriptional patterns.
Alissa D. Guarnaccia, April M. Weissmiller, William P. Tansey   +2 more
doaj   +1 more source

Complete mitochondrial genome of the freshwater prawn Palaemon capensis (Crustacea: Palaemonidae)

Mitochondrial DNA. Part B. Resources, 2017
The complete mitogenome of Palaemon capensis is presented here. The mitogenome is 15,925 bp in length and comprises 13 protein coding genes, 2 ribosomal subunit genes, 22 transfer RNAs, and a non-coding AT-rich region.
Louisa E. Wood, Sammy De Grave, Carel J. van Heerden, Savel R. Daniels   +3 more
doaj   +1 more source

Medical DNA sequencing [PDF]

Current Opinion in Cardiology, 2011
To discuss implications of information garnered through whole-genome and exome sequencing in the practice of cardiovascular medicine.Whole-genome and exome sequencing unveils medical information embedded in individual genomes and exomes, which could be incorporated into the practice of medicine for diagnostic and therapeutic gains.
openaire   +2 more sources

Correction to: A new species of Xenoturbella from the western Pacific Ocean and the evolution of Xenoturbella

BMC Evolutionary Biology, 2018
After publication of Nakano et al. (2017) [1], the authors became aware of the fact that the new species-group name erected for the two specimens of a Japanese xenoturbellid species in the article is not available because Nakano et al.
Hiroaki Nakano, Hideyuki Miyazawa, Akiteru Maeno, Toshihiko Shiroishi, Keiichi Kakui, Ryo Koyanagi, Miyuki Kanda, Noriyuki Satoh, Akihito Omori, Hisanori Kohtsuka   +9 more
doaj   +1 more source

A new species of Xenoturbella from the western Pacific Ocean and the evolution of Xenoturbella

BMC Evolutionary Biology, 2017
Background Xenoturbella is a group of marine benthic animals lacking an anus and a centralized nervous system. Molecular phylogenetic analyses group the animal together with the Acoelomorpha, forming the Xenacoelomorpha.
Hiroaki Nakano, Hideyuki Miyazawa, Akiteru Maeno, Toshihiko Shiroishi, Keiichi Kakui, Ryo Koyanagi, Miyuki Kanda, Noriyuki Satoh, Akihito Omori, Hisanori Kohtsuka   +9 more
doaj   +1 more source

Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progressionResearch in context

EBioMedicine, 2019
Background: Several publications have described differences in cross-sectional comparisons of gut microbiota between patients with Parkinson's disease and control subjects, with considerable variability of the reported differentially abundant taxa.
Velma T.E. Aho, Pedro A.B. Pereira, Sari Voutilainen, Lars Paulin, Eero Pekkonen, Petri Auvinen, Filip Scheperjans   +6 more
doaj   +1 more source

Fecal microbiome alterations in treatment-naive de novo Parkinson’s disease

npj Parkinson's Disease, 2022
Gut microbiota alterations in Parkinson’s disease (PD) have been found in several studies and are suggested to contribute to the pathogenesis of PD.
Jeffrey M. Boertien, Kirsi Murtomäki, Pedro A. B. Pereira, Sygrid van der Zee, Tuomas H. Mertsalmi, Reeta Levo, Tanja Nojonen, Elina Mäkinen, Elina Jaakkola, Pia Laine, Lars Paulin, Eero Pekkonen, Valtteri Kaasinen, Petri Auvinen, Filip Scheperjans, Teus van Laar, PPNN Study Group   +16 more
doaj   +1 more source

High‐throughput sequencing approach in analysis of microbial communities colonizing natural gas pipelines

MicrobiologyOpen, 2019
This study provides a deep modern insight into the phylogenetic diversity among bacterial consortia found in working and nonworking high‐methane natural gas pipelines located in Poland.
Agnieszka Staniszewska, Alina Kunicka‐Styczyńska, Anna Otlewska, Jan Gawor, Robert Gromadka, Karolina Żuchniewicz, Krzysztof Ziemiński   +6 more
doaj   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior   +9 more
wiley   +1 more source