Results 21 to 30 of about 1,741,840 (332)
PLoS ONE, 2013 Data summarization and triage is one of the current top challenges in visual analytics. The goal is to let users visually inspect large data sets and examine or request data with particular characteristics. The need for summarization and visual analytics is also felt when dealing with digital representations of DNA sequences.
Armando J. Pinho +3 more
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Exoquence DNA sequencing [PDF]
Nucleic Acids Research, 1993 We have developed a strategy for DNA sequencing based on exonuclease III digestion followed by double strand specific endonuclease digestion and direct dideoxynucleotide sequencing reaction. This strategy eliminates the need for subcloning, oligonucleotide primers, and prior knowledge of the DNA to be sequenced.
Chuan Li, Philip W. Tucker
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Comparative genomics of four strains of the edible brown alga, Cladosiphon okamuranus
BMC Genomics, 2020 Background The brown alga, Cladosiphon okamuranus (Okinawa mozuku), is one of the most important edible seaweeds, and it is cultivated for market primarily in Okinawa, Japan.
Koki Nishitsuji +7 more
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Identification of single nucleotides in MoS2 nanopores [PDF]
, 2015 Ultrathin membranes have drawn much attention due to their unprecedented spatial resolution for DNA nanopore sequencing. However, the high translocation velocity (3000-50000 nt/ms) of DNA molecules moving across such membranes limits their usability.
Bulushev, Roman D. +6 more
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Medical Hypotheses, 2000 A method for fast nucleotide sequencing is described. It is based in the selection of well-known small oligomers able to be hybridized with the unknown target. The selected oligomers are afterwards ordered following a simple statistical approach. The use of capillary electrophoresis for the analysis is emphasized.
Figureau, A., Soto, M.A., Toha, J.
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16S rRNA gene sequencing of mock microbial populations- impact of DNA extraction method, primer choice and sequencing platform [PDF]
, 2016 peer-reviewedBackground Next-generation sequencing platforms have revolutionised our ability to investigate the microbiota composition of complex environments, frequently through 16S rRNA gene sequencing of the bacterial component of the
Claesson, Marcus J. +4 more
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Functionalized nanopore-embedded electrodes for rapid DNA sequencing [PDF]
, 2007 The determination of a patient's DNA sequence can, in principle, reveal an increased risk to fall ill with particular diseases [1,2] and help to design "personalized medicine" [3].
Ahuja, Rajeev +7 more
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ELECTROPHORESIS, 2009 AbstractSequencing of human and other genomes has been at the center of interest in the biomedical field over the past several decades and is now leading toward an era of personalized medicine. During this time, DNA‐sequencing methods have evolved from the labor‐intensive slab gel electrophoresis, through automated multiCE systems using fluorophore ...
András Guttman, Barry L. Karger
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Molecular Therapy: Methods & Clinical Development, 2022 With the aim of expediting drug target discovery and validation for respiratory diseases, we developed an optimized method for in situ somatic gene disruption in murine lung epithelial cells via AAV6-mediated CRISPR-Cas9 delivery.
Honglin Chen +13 more
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Highly accurate long reads are crucial for realizing the potential of biodiversity genomics
BMC Genomics, 2023 Background Generating the most contiguous, accurate genome assemblies given available sequencing technologies is a long-standing challenge in genome science.
Scott Hotaling +4 more
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