VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research [PDF]
, 2016 Accurate variant calling in next generation sequencing (NGS) is critical to understand cancer genomes better. Here we present VarDict, a novel and versatile variant caller for both DNA- and RNA-sequencing data.
Ahdesmaki, Miika +9 more
core +2 more sources
Optimization of DNA extraction from human urinary samples for mycobiome community profiling. [PDF]
, 2019 IntroductionRecent data suggest the urinary tract hosts a microbial community of varying composition, even in the absence of infection. Culture-independent methodologies, such as next-generation sequencing of conserved ribosomal DNA sequences, provide an
Ackerman, A Lenore +8 more
core +3 more sources
High-throughput DNA sequencing to survey bacterial histidine and tyrosine decarboxylases in raw milk cheeses [PDF]
, 2015 peer-reviewedBackground The aim of this study was to employ high-throughput DNA sequencing to assess the incidence of bacteria with biogenic amine (BA; histamine and tyramine) producing potential from among 10 different cheeses varieties.
Cotter, Paul D. +6 more
core +1 more source
Highly accurate long reads are crucial for realizing the potential of biodiversity genomics
BMC Genomics, 2023 Background Generating the most contiguous, accurate genome assemblies given available sequencing technologies is a long-standing challenge in genome science.
Scott Hotaling +4 more
doaj +1 more source
STAR Protocols, 2021 Summary: Genome-wide nuclear run-ons are a powerful way to determine the impact of a perturbation such as transcription factor degradation on transcriptional patterns.
Alissa D. Guarnaccia +2 more
doaj +1 more source
Complete mitochondrial genome of the freshwater prawn Palaemon capensis (Crustacea: Palaemonidae)
Mitochondrial DNA. Part B. Resources, 2017 The complete mitogenome of Palaemon capensis is presented here. The mitogenome is 15,925 bp in length and comprises 13 protein coding genes, 2 ribosomal subunit genes, 22 transfer RNAs, and a non-coding AT-rich region.
Louisa E. Wood +3 more
doaj +1 more source
Current Opinion in Cardiology, 2011 To discuss implications of information garnered through whole-genome and exome sequencing in the practice of cardiovascular medicine.Whole-genome and exome sequencing unveils medical information embedded in individual genomes and exomes, which could be incorporated into the practice of medicine for diagnostic and therapeutic gains.
openaire +2 more sources
Molecular genotyping of multi-system rare blood types in foreign blood donors based on DNA sequencing and its clinical significance [PDF]
Open Med (Wars)Jianli Gong, Xianguo Xu, Jianrong Zhu
openalex +2 more sources
A new species of Xenoturbella from the western Pacific Ocean and the evolution of Xenoturbella
BMC Evolutionary Biology, 2017 Background Xenoturbella is a group of marine benthic animals lacking an anus and a centralized nervous system. Molecular phylogenetic analyses group the animal together with the Acoelomorpha, forming the Xenacoelomorpha.
Hiroaki Nakano +9 more
doaj +1 more source
An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing. [PDF]
, 2018 Sequencing technologies have undergone a paradigm shift from bulk to single-cell resolution in response to an evolving understanding of the role of cellular heterogeneity in biological systems.
Abate, Adam R +3 more
core +2 more sources