Results 61 to 70 of about 17,272 (247)
MicroRNAs and Epigenetics Strategies to Reverse Breast Cancer
Cells, 2019 Breast cancer is a sporadic disease with genetic and epigenetic components. Genomic instability in breast cancer leads to mutations, copy number variations, and genetic rearrangements, while epigenetic remodeling involves alteration by DNA methylation ...
Mohammad Mijanur Rahman +2 more
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Module-based construction of plasmids for chromosomal integration of the fission yeast Schizosaccharomyces pombe [PDF]
Open Biology, 2015 Integration of an external gene into a fission yeast chromosome is useful to investigate the effect of the gene product. An easy way to knock-in a gene construct is use of an integration plasmid, which can be targeted and inserted to a chromosome through
Yasutaka Kakui +7 more
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Correcting errors in synthetic DNA through consensus shuffling [PDF]
Nucleic Acids Research, 2005 Although efficient methods exist to assemble synthetic oligonucleotides into genes and genomes, these suffer from the presence of 1-3 random errors/kb of DNA. Here, we introduce a new method termed consensus shuffling and demonstrate its use to significantly reduce random errors in synthetic DNA.
Binkowski, Brock F. +4 more
openaire +2 more sources
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
The complete mitochondrial genome of Cynoglossus joyneri and its novel rearrangement
Mitochondrial DNA. Part B. Resources, 2017 The complete mitochondrial genome of Cynoglossus joyneri was determined. The length of the C. joyneri complete mitochondrial DNA sequence is 16,428 bp.
Zhang Bo +3 more
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Random Shuffling Permutations of Nucleotides [PDF]
Journal of Systemics, Cybernetics and Informatics, 2003 In this paper, we discuss a shuffling sequence problem: Given a DNA sequence, we generate a random sequence that preserves the frequencies of all mononucleotides, dinucleotides, trinucleotides or some high order base-compositions of the given sequence ...
Shiquan Wu, Xun Gu
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GATA: a graphic alignment tool for comparative sequence analysis
BMC Bioinformatics, 2005 Background Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved sequence elements are collinear.
Nix David A, Eisen Michael B
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Tracing the
mBio, 2018 De novo genes are very important for evolutionary innovation. However, how these genes originate and spread remains largely unknown. To better understand this, we rigorously searched for de novo genes in Saccharomyces cerevisiae S288C and examined their ...
Baojun Wu, Alicia Knudson
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