Results 81 to 90 of about 34,995 (285)
Which way up? Recognition of homologous DNA segments in parallel and antiparallel alignment
, 2014 Homologous gene shuffling between DNA promotes genetic diversity and is an important pathway for DNA repair. For this to occur, homologous genes need to find and recognize each other.
Aaron Wynveen +6 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
MicroRNAs and Epigenetics Strategies to Reverse Breast Cancer
Cells, 2019 Breast cancer is a sporadic disease with genetic and epigenetic components. Genomic instability in breast cancer leads to mutations, copy number variations, and genetic rearrangements, while epigenetic remodeling involves alteration by DNA methylation ...
Mohammad Mijanur Rahman +2 more
doaj +1 more source
Module-based construction of plasmids for chromosomal integration of the fission yeast Schizosaccharomyces pombe [PDF]
Open Biology, 2015 Integration of an external gene into a fission yeast chromosome is useful to investigate the effect of the gene product. An easy way to knock-in a gene construct is use of an integration plasmid, which can be targeted and inserted to a chromosome through
Yasutaka Kakui +7 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The complete mitochondrial genome of Cynoglossus joyneri and its novel rearrangement
Mitochondrial DNA. Part B. Resources, 2017 The complete mitochondrial genome of Cynoglossus joyneri was determined. The length of the C. joyneri complete mitochondrial DNA sequence is 16,428 bp.
Zhang Bo +3 more
doaj +1 more source
Different Approaches For Protein Engineering In Industrial Biotechnology [PDF]
, 2011 Protein engineering is the novel field which has wide applications from pharmaceutics, industry, commercial, laundry and research. It may apply rational design or non rational design or both.
Israr Khan, Muhammad Waheed Akhtar
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Random Shuffling Permutations of Nucleotides [PDF]
Journal of Systemics, Cybernetics and Informatics, 2003 In this paper, we discuss a shuffling sequence problem: Given a DNA sequence, we generate a random sequence that preserves the frequencies of all mononucleotides, dinucleotides, trinucleotides or some high order base-compositions of the given sequence ...
Shiquan Wu, Xun Gu
doaj
GATA: a graphic alignment tool for comparative sequence analysis
BMC Bioinformatics, 2005 Background Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved sequence elements are collinear.
Nix David A, Eisen Michael B
doaj +1 more source