Results 101 to 110 of about 699,352 (277)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A Novel DNA‐Based Dual‐Mode Data Storage System with Interrelated Concise and Detailed Data
Small ScienceDNA has emerged as a promising storage medium to meet the soaring need for archival data storage because of its exceptional storage density and stability.
Ben Pei +8 more
doaj +1 more source
DSI-ResCNN: A Framework Enhancing the Error-Tolerance Capacity of DNA Storage for Images
IEEE AccessTraditional silicon-based storage technologies have reached a bottleneck with the dramatic increase in global data storage demands. High energy consumption, limited natural resources, and environmental concerns are some of the key reasons.
Cihan Ruan +7 more
doaj +1 more source
DNA-Correcting Codes in DNA Storage Systems
, 2023 In [1], the authors proposed a new model of DNA storage system that integrates all three steps of retrieval and introduced the concept of DNA-correcting codes, which guarantees that the output of the storage system can be decoded to the original data. They also gave necessary and sufficient conditions for DNA-correcting codes when the data part is free
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Experimental DNA storage platform
, 2022 The dnarXiv projects 1 aims to explore various strategies for DNA storage. We have designed an experimental DNA storage platform allowing both to conduct real and/or in-silico experiments. The platform includes different modules generally used in the write/read DNA storage process: encoding, synthesis, molecule design, storage, molecule selection ...
Boullé, Olivier, Lavenier, Dominique
openaire +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Thyroid Hormone as a Method of Reducing Damage to Donor Hearts after Circulatory Arrest [PDF]
, 2017 There is a chronic lack of donor hearts to meet the need for heart transplant both in the US and worldwide. Further, the use of available hearts is limited by the short period between collection and implantation during which the heart can be safely ...
Adams, William P.
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source