Results 121 to 130 of about 3,302,587 (288)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Molecular associative memory: An associative memory framework with exponential storage capacity for DNA computing [PDF]

open access: yes
Associative memory problem: Find the closest stored vector (in Hamming distance) to a given query vector. There are different ways to implement an associative memory, including the neural networks and DNA strands.
Salavati, Amir Hesam   +2 more
core   +1 more source

Functional mapping of pea legumin upstream regulatory elements using TI plasmid vectors [PDF]

open access: yes, 1991
The leg A gene from Pisum sativum L. has been extensively characterised and a distinct pattern of developmental and organ-specific gene expression demonstrated.
Garrett, Christine, Garrett, C
core  

Linked data storage using DNA origami nanostructures

open access: yesNature Communications
DNA-based storage is an alternative solution for archiving vast cold data. Its future development aims to meet the demands of hot data storage, which requires rapid random access and efficient data modification.
Chenhao Zhang   +4 more
doaj   +1 more source

High information capacity DNA-based data storage with augmented encoding characters using degenerate bases

open access: yesScientific Reports, 2019
DNA-based data storage has emerged as a promising method to satisfy the exponentially increasing demand for information storage. However, practical implementation of DNA-based data storage remains a challenge because of the high cost of data writing ...
Yeongjae Choi   +10 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Basecalling for DNA Storage

open access: yes
Abstract DNA is a promising medium for data storage with its high information density and stability. To retrieve information stored in DNA, sequencing technologies are used to read the encoded bases. The raw signals from sequencing are mapped to a sequence of {A,C,T,G} by machine learning algorithms known as basecallers.
Advait Menon   +3 more
openaire   +1 more source

Primer‐Disk‐Enabled DNA Data Storage System with Index and Record‐Many‐Read‐Many Features

open access: yesAdvanced Science
DNA data storage has emerged as a promising information storage technology by encoding information down to base molecules. However, it remains a challenge to structure the DNA data with ease of recording, retrieving, and reading.
Jiaxiang Ma   +5 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

VSD: A Novel Method for Video Segmentation and Storage in DNA Using RS Code

open access: yesMathematics
As data continue to grow in complexity and size, there is an imperative need for more efficient and robust storage solutions. DNA storage has emerged as a promising avenue to solve this problem, but existing approaches do not perform efficiently enough ...
Jingwei Hong   +4 more
doaj   +1 more source

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