Results 91 to 100 of about 2,195,182 (275)

High‐Efficiency Quantum Defect Generation in Carbon Nanotubes via Oxygen‐Free Photochemistry

Advanced Functional Materials, EarlyView.
We show that oxygen plays an important role in quantum defect formation in carbon nanotubes and identify reaction conditions to create a range of different quantum defects for photonics and biosensing. ABSTRACT Single‐walled carbon nanotubes (SWCNTs) offer potential for a wide range of applications from optoelectronic devices to biomedical diagnostics.
Christina Derichsweiler, Valeriia D. Andreeva, Jan Stegemann, Julia Ackermann, Janus A. C. Wartmann, Svenja Herbertz, Sebastian Kruss   +6 more
wiley   +1 more source

Integrating DNA-Strand-Displacement Circuitry with Self-Assembly of Spherical Nucleic Acids

, 2015
Programmable and algorithmic behaviors of DNA molecules allow one to control the structures of DNA-assembled materials with nanometer precision and to construct complex networks with digital and analog behaviors.
Shiyan Xiao (443389), Tingjie Song (1485958), Xianbao Sun (1485961), Haojun Liang (105234), Fujian Huang (1328148), Dongbao Yao (1485955)   +5 more
core   +1 more source

Structural mechanism of strand exchange by the RAD51 filament

eLife
Homologous recombination (HR) preserves genomic stability by repairing double-strand DNA breaks and ensuring efficient DNA replication. Central to HR is the strand-exchange reaction taking place within the three-stranded synapsis wherein a RAD51 ...
Luay Joudeh, Robert E Appleby, Joseph D Maman, Luca Pellegrini   +3 more
doaj   +1 more source

High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis

Nature Communications, 2019
Current DNA computational systems are constrained by integration efficiency, device structures and limited functions. Here the authors design a DNA arithmetic logic unit that uses polymerase-mediated strand displacement.
Haomiao Su, Jinglei Xu, Qi Wang, Fuan Wang, Xiang Zhou   +4 more
doaj   +1 more source

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform

Advanced Healthcare Materials, EarlyView.
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu, Xinggui Tian, Anne Bernhardt, Anja Lode, Max von Witzleben, Ege Kirbas, Stefan Zwingenberger, Michael Gelinsky   +7 more
wiley   +1 more source

Targeting the DNA double strand break repair machinery in prostate cancer [PDF]

, 2011
Regardless of the achievable remissions with first line hormone therapy in patients with prostate cancer (CaP), the disease escapes the hormone dependent stage to a more aggressive status where chemotherapy is the only effective treatment and no ...
Fadhel S. Shaheen, Pawel Znojek, Fisher Ann, Robson Craig N., Graeme C M Smith, Leung, H.Y., Nicola J Curtin, Craig N. Robson, Martin Webster, Znojek Pawel, Plummer Ruth, Curtin Nicola J., Gaughan, L., Curtin, N.J., Smith, G.C. M., Ruth Plummer, Fadhel S Shaheen, Craig N Robson, Shaheen Fadhel S., Smith Graeme C. M., Nicola J. Curtin, Robson, C.N., Plummer, R., Ann Fisher, Gaughan Luke, Webster, M., Znojek, P., Hing Y. Leung, Shaheen, F.S., Fisher, A., Hing Y Leung, Webster Martin, Luke Gaughan, Leung Hing Y., Graeme C. M. Smith   +34 more
core   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Kinetics of Proximity-Induced Intramolecular DNA Strand Displacement

, 2016
Proximity-induced intramolecular DNA strand displacement (PiDSD) is one of the key mechanisms involved in many DNA-mediated proximity assays and protein-responsive DNA devices.
Yanan Tang (813663), Sarah M. Traynor (2908211), X. Chris Le (17762), Feng Li (30515), Xing-Fang Li (61783)   +4 more
core   +1 more source

Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism [PDF]

, 2005
The established strand-displacement model for mammalian mitochondrial DNA (mtDNA) replication has recently been questioned in light of new data using two-dimensional (2D) agarose gel electrophoresis.
Tkachuk, An, Clayton, Da, Brown, Ta, CECCONI, CIRO, Bustamante, C   +4 more
core   +1 more source