Results 211 to 220 of about 35,316 (244)

Performing DNA Strand Displacement with DNA Polymerase

2020
Significant improvements to the dynamic DNA nano science have emerged in recent years, primarily due to the elaborate design of toehold-mediated DNA strand displacement (TMSD). However, it remains an ongoing challenge to design huge-scaled TMSD based sophisticated dynamic DNA structures without base-pair mismatching or unwanted secondary structures ...
Zhiyu Wang, Yingxin Hu, Zhekun Chen, Sulin Liao, Yabing Huang   +4 more
openaire   +1 more source

Analog Computation by DNA Strand Displacement Circuits

ACS Synthetic Biology, 2016
DNA circuits have been widely used to develop biological computing devices because of their high programmability and versatility. Here, we propose an architecture for the systematic construction of DNA circuits for analog computation based on DNA strand displacement.
Tianqi, Song, Sudhanshu, Garg, Reem, Mokhtar, Hieu, Bui, John, Reif   +4 more
openaire   +2 more sources

Circular DNA Logic Gates with Strand Displacement

Langmuir, 2009
Circular DNA logic gates were constructed on the basis of DNA three-way branch migration. In this logic system, circular DNA was used as a basic work unit and linear single-strand DNA was used as input and output signals. Making use of the circular structure, most of the DNA-specific recognition regions were designed in a single DNA ring.
Cheng, Zhang, Jing, Yang, Jin, Xu
openaire   +2 more sources

Connecting localized DNA strand displacement reactions

Nanoscale, 2015
Design and characterization of a DNA-based localized amplification circuit which, upon tethering on a DNA origami platform, greatly accelerates the catalytic response.
Ismael Mullor, Ruiz, Jean-Michel, Arbona, Amitkumar, Lad, Oscar, Mendoza, Jean-Pierre, Aimé, Juan, Elezgaray   +5 more
openaire   +2 more sources

Autonomous Resolution Based on DNA Strand Displacement

2011
We present a computing model based on the technique of DNA strand displacement which performs a chain of logical resolutions with logical formulae in conjunctive normal form. The model is enzymefree and autonomous. Each clause of a formula is encoded in a separate DNA molecule: propositions are encoded assigning a strand to each proposition p, and its ...
Alfonso Rodríguez-Patón, Iñaki Sainz de Murieta, Petr Sosík   +2 more
openaire   +1 more source

Regulation of DNA Strand Displacement Using an Allosteric DNA Toehold

Journal of the American Chemical Society, 2016
Toehold-mediated DNA strand displacement is the fundamental basis for the construction and operation of diverse DNA devices, including circuits, machines, sensors, and reconfigurable structures. Controllable activation and regulation of toeholds are critical to construct devices with multistep, autonomous, and complex behaviors.
Xiaolong, Yang, Yanan, Tang, Sarah M, Traynor, Feng, Li   +3 more
openaire   +2 more sources

DNA Kirigami Driven by Polymerase‐Triggered Strand Displacement

Small, 2022
AbstractThe precursors of functional biomolecules in living cells are synthesized in a bottom‐up manner and subsequently activated by modification into a delicate structure with near‐atomic precision. DNA origami technology provides a promising way to mimic the synthesis of precursors, although mimicking the modification process is a challenge. Herein,
Kuiting Chen, Fei Xu, Yingxin Hu, Hao Yan, Linqiang Pan   +4 more
openaire   +2 more sources

Mechanism of DNA multimerization caused by strand-displacement DNA polymerases

Analytical Biochemistry
It has been recently shown that for Bst DNA polymerase, the side isothermal amplification reaction named multimerization (MM) proceeds under certain conditions. MM hinders interpretation of amplification results and reduces the accuracy and reliability of DNA/RNA diagnostics.
Assol R. Sakhabutdinova, Ravil R. Garafutdinov   +1 more
openaire   +2 more sources

Base Conversion Model Based on DNA Strand Displacement

2020
DNA computing has the advantages of high parallelism and large storage. In this paper, DNA strand displacement techniques are applied to binary to decimal system. In the field of DNA calculation, binary numerical calculation is relatively mature, but it is difficult to implement decimal calculation.
Zhao Chen, Zhixiang Yin, Jianzhong Cui, Zhen Tang, Qiang Zhang 0008   +4 more
openaire   +1 more source

Dynamic DNA nanotechnology using strand-displacement reactions

Nature Chemistry, 2011
The specificity and predictability of Watson-Crick base pairing make DNA a powerful and versatile material for engineering at the nanoscale. This has enabled the construction of a diverse and rapidly growing set of DNA nanostructures and nanodevices through the programmed hybridization of complementary strands.
David Yu, Zhang, Georg, Seelig
openaire   +2 more sources