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Dynamic DNA nanotechnology using strand-displacement reactions
Nature Chemistry, 2011The specificity and predictability of Watson-Crick base pairing make DNA a powerful and versatile material for engineering at the nanoscale. This has enabled the construction of a diverse and rapidly growing set of DNA nanostructures and nanodevices through the programmed hybridization of complementary strands.
David Yu, Zhang, Georg, Seelig
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Tracking DNA Synthesis with Single-Molecule Strand Displacement
The Journal of Physical Chemistry B, 2018We have previously shown that double-stranded DNA labeled with a periodic series of fluorescent dyes can be used to track a single helicase. Here we demonstrate how this technique can be adapted to follow processive DNA synthesis. By monitoring strand displacement, we track the motion of a single ϕ29 DNA polymerase without labeling or altering the ...
Charles E. Wickersham, Everett A. Lipman
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Dynamic protein assembly by programmable DNA strand displacement
Nature Chemistry, 2018Inspired by the remarkable ability of natural protein switches to sense and respond to a wide range of environmental queues, here we report a strategy to engineer synthetic protein switches by using DNA strand displacement to dynamically organize proteins with highly diverse and complex logic gate architectures. We show that DNA strand displacement can
Rebecca P. Chen +3 more
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Chaperone‐Polymer‐Assisted, Photodriven DNA Strand Displacement
ChemBioChem, 2017AbstractPhotodriven DNA strand displacement by using a 2′,6′‐dimethylazobenzene‐tethered strand and poly(l‐lysine)‐graft‐dextran (PLL‐g‐Dex) as a chaperone is reported. Rapid strand displacement was reversibly induced by UV and visible‐light irradiation without any toehold portion.
Bohao Cheng +4 more
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DNA strand displacement reaction for programmable release of biomolecules
Chemical Communications, 2015The DNA strand displacement reaction (SDR) was successfully combined with a fluoroimmunoassay on silica microparticles to accomplish sequence-specific release,in situsample cleanup, and buffer exchange.
Hamid, Ramezani, D, Jed Harrison
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Dynamic DNA Strand Displacement Circuits
2010Nucleic acids, the "NA" in DNA and RNA, have long been known to be vitally important molecules within biological cells and organisms. However, they are interesting for more than just their known roles in biology: their predictable Watson-Crick base pairing properties allow nucleic acids to be powerful nanoscale engineering tools.
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Base Conversion Model Based on DNA Strand Displacement
2020DNA computing has the advantages of high parallelism and large storage. In this paper, DNA strand displacement techniques are applied to binary to decimal system. In the field of DNA calculation, binary numerical calculation is relatively mature, but it is difficult to implement decimal calculation.
Zhao Chen +4 more
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Cooperative Branch Migration: A Mechanism for Flexible Control of DNA Strand Displacement
ACS Nano, 2022Zhi Weng, Qian Liu, Zhang Zhang
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Encryption Algorithm Based on DNA Strand Displacement and DNA Sequence Operation
IEEE Transactions on Nanobioscience, 2021Chengye Zou +2 more
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Kinetics of RNA and RNA:DNA Hybrid Strand Displacement
ACS Synthetic Biology, 2021Fan Hong +2 more
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