Results 271 to 280 of about 78,386 (303)
Some of the next articles are maybe not open access.
Heterochiral DNA Strand-Displacement Circuits
Journal of the American Chemical Society, 2017The absence of a straightforward strategy to interface native d-DNA with its enantiomer l-DNA-oligonucleotides of opposite chirality are incapable of forming contiguous Watson-Crick base pairs with each other-has enforced a "homochiral" paradigm over the field of dynamic DNA nanotechnology.
Adam M. Kabza +2 more
openaire +2 more sources
Robustness of Localized DNA Strand Displacement Cascades
ACS Nano, 2014Colocalization can strongly alter the kinetics and efficiency of chemical processes. For instance, in DNA-templated synthesis unfavorable reactions are sped up by placing reactants into close proximity onto a DNA scaffold. In biochemistry, clustering of enzymes has been demonstrated to enhance the reaction flux through some enzymatic cascades.
Enzo Kopperger, Friedrich C Simmel
exaly +3 more sources
DNA Strand-Displacement Timer Circuits
ACS Synthetic Biology, 2016Chemical circuits can coordinate elaborate sequences of events in cells and tissues, from the self-assembly of biological complexes to the sequence of embryonic development. However, autonomously directing the timing of events in synthetic systems using chemical signals remains challenging.
Joshua, Fern +5 more
openaire +2 more sources
Performing DNA Strand Displacement with DNA Polymerase
2020Significant improvements to the dynamic DNA nano science have emerged in recent years, primarily due to the elaborate design of toehold-mediated DNA strand displacement (TMSD). However, it remains an ongoing challenge to design huge-scaled TMSD based sophisticated dynamic DNA structures without base-pair mismatching or unwanted secondary structures ...
Zhiyu Wang +4 more
openaire +1 more source
Analog Computation by DNA Strand Displacement Circuits
ACS Synthetic Biology, 2016DNA circuits have been widely used to develop biological computing devices because of their high programmability and versatility. Here, we propose an architecture for the systematic construction of DNA circuits for analog computation based on DNA strand displacement.
Tianqi, Song +4 more
openaire +2 more sources
Connecting localized DNA strand displacement reactions
Nanoscale, 2015Design and characterization of a DNA-based localized amplification circuit which, upon tethering on a DNA origami platform, greatly accelerates the catalytic response.
Ismael Mullor, Ruiz +5 more
openaire +2 more sources
Circular DNA Logic Gates with Strand Displacement
Langmuir, 2009Circular DNA logic gates were constructed on the basis of DNA three-way branch migration. In this logic system, circular DNA was used as a basic work unit and linear single-strand DNA was used as input and output signals. Making use of the circular structure, most of the DNA-specific recognition regions were designed in a single DNA ring.
Cheng, Zhang, Jing, Yang, Jin, Xu
openaire +2 more sources
Autonomous Resolution Based on DNA Strand Displacement
2011We present a computing model based on the technique of DNA strand displacement which performs a chain of logical resolutions with logical formulae in conjunctive normal form. The model is enzymefree and autonomous. Each clause of a formula is encoded in a separate DNA molecule: propositions are encoded assigning a strand to each proposition p, and its ...
Alfonso Rodríguez-Patón +2 more
openaire +1 more source
Regulation of DNA Strand Displacement Using an Allosteric DNA Toehold
Journal of the American Chemical Society, 2016Toehold-mediated DNA strand displacement is the fundamental basis for the construction and operation of diverse DNA devices, including circuits, machines, sensors, and reconfigurable structures. Controllable activation and regulation of toeholds are critical to construct devices with multistep, autonomous, and complex behaviors.
Xiaolong, Yang +3 more
openaire +2 more sources
DNA strand displacement system running logic programs
Biosystems, 2014The paper presents a DNA-based computing model which is enzyme-free and autonomous, not requiring a human intervention during the computation. The model is able to perform iterated resolution steps with logical formulae in conjunctive normal form. The implementation is based on the technique of DNA strand displacement, with each clause encoded in a ...
Alfonso Rodríguez-Patón +2 more
openaire +2 more sources