Results 11 to 20 of about 230,805 (269)

The dynamic interplay between DNA topoisomerases and DNA topology [PDF]

Biophysical Reviews, 2016
Topological properties of DNA influence its structure and biochemical interactions. Within the cell DNA topology is constantly in flux. Transcription and other essential processes including DNA replication and repair, alter the topology of the genome, while introducing additional complications associated with DNA knotting and catenation.
Keir C Neuman
exaly   +10 more sources

Nucleosomal DNA has topological memory

Nature Communications
One elusive aspect of the chromosome architecture is how it constrains the DNA topology. Nucleosomes stabilise negative DNA supercoils by restraining a DNA linking number difference (∆Lk) of about −1.26.
Joana Segura, Ofelia Díaz-Ingelmo, Belén Martínez-García, Alba Ayats-Fraile, Christoforos Nikolaou, Joaquim Roca   +5 more
doaj   +4 more sources

Regulation of DNA Topology in Archaea: State of the Art and Perspectives [PDF]

Molecular Microbiology
Tamara Basta
exaly   +2 more sources

Topogami: Topologically Linked DNA Origami [PDF]

ACS Nanoscience Au, 2021
DNA origami is a widely used DNA nanotechnology that allows construction of two-dimensional and three-dimensional nanometric shapes. The designability and rigidity of DNA origami make it an ideal material for construction of topologically linked molecules such as catenanes, which are attractive for their potential as motors and molecular machines ...
Yusuke Sakai, Gerrit D. Wilkens, Karol Wolski, Szczepan Zapotoczny, Jonathan G. Heddle   +4 more
openaire   +3 more sources

A review on nonlinear DNA physics [PDF]

Royal Society Open Science, 2020
The study and the investigation of structural and dynamical properties of complex systems have attracted considerable interest among scientists in general and physicists and biologists in particular.
Dalibor Chevizovich, Davide Michieletto, Alain Mvogo, Farit Zakiryanov, Slobodan Zdravković   +4 more
doaj   +1 more source

DNA topology and transcription. [PDF]

Nucleus, 2014
Chromatin is a complex assembly that compacts DNA inside the nucleus while providing the necessary level of accessibility to regulatory factors conscripted by cellular signaling systems. In this superstructure, DNA is the subject of mechanical forces applied by variety of molecular motors.
Kouzine F, Levens D, Baranello L.
europepmc   +4 more sources

Data of transcriptional effects of the merbarone-mediated inhibition of TOP2

Data in Brief, 2022
Type II DNA topoisomerases relax topological stress by transiently gating DNA passage in a controlled cut-and-reseal mechanism that affects both DNA strands.
Fernando M. Delgado-Chaves, Pedro Manuel Martínez-García, Andrés Herrero-Ruiz, Francisco Gómez-Vela, Federico Divina, Silvia Jimeno-González, Felipe Cortés-Ledesma   +6 more
doaj   +1 more source

Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays [PDF]

Journal of Biological Chemistry, 2019
Davood Norouzi, Victor B Zhurkin, Sergei A Grigoryev   +2 more
exaly   +2 more sources

TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection [PDF]

Molecular Cell, 2016
Delphine Benarroch-Popivker, Sabrina Pisano, Aaron Mendez-Bermudez   +2 more
exaly   +2 more sources

The Effect of DNA Topology on Observed Rates of R-Loop Formation and DNA Strand Cleavage by CRISPR Cas12a [PDF]

Genes, 2019
Stephen J Cross, Mark D Szczelkun
exaly   +2 more sources