Results 11 to 20 of about 124,583 (279)

DNA Topology: Dynamic DNA Looping [PDF]

open access: yesCurrent Biology, 2006
The DNA in repressive loops is often tightly bent. DNA flexibility imposes significant constraints on their topology suggesting that they may exist as perturbations in plectonemic DNA.
Travers, Andrew
openaire   +3 more sources

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology [PDF]

open access: yesCell Reports, 2015
Toxin-antitoxin (TA) modules are ubiquitous molecular switches controlling bacterial growth via the release of toxins that inhibit cell proliferation.
Alexander Harms   +8 more
doaj   +2 more sources

Applications of topology to DNA [PDF]

open access: yesBanach Center Publications, 1998
0. Some preliminaries. Many biological processes affect topological properties of DNA. Duplex DNA consists of two backbone strands wound about each other in a righthanded helical fashion. Each strand consists of a sugar phosphate backbone with a nitrogenous base attached to each sugar. The four possible bases are adenine (A), guanine (G), cytosine (C),
De Sumners, Isabel Darcy
openaire   +2 more sources

Editorial: Chromosome architecture and DNA topology in prokaryotes [PDF]

open access: yesFrontiers in Microbiology, 2023
Tamara Basta   +2 more
doaj   +2 more sources

Effect of DNA topology on plasmid DNA repair in vivo

open access: yesFEBS Letters, 2000
Escherichia coli nucleotide excision repair (NER) is responsible for removing bulky DNA adducts by dual incisions of the UvrABC endonuclease. Although the activity of the UvrAB complex which can induce DNA conformational change is employed in NER, the involvement of DNA topology and DNA topoisomerases remains unclear.
Park, Jik-Young, Ahn, Byungchan
openaire   +3 more sources

A review on nonlinear DNA physics [PDF]

open access: yesRoyal Society Open Science, 2020
The study and the investigation of structural and dynamical properties of complex systems have attracted considerable interest among scientists in general and physicists and biologists in particular.
Dalibor Chevizovich   +4 more
doaj   +1 more source

Data of transcriptional effects of the merbarone-mediated inhibition of TOP2

open access: yesData in Brief, 2022
Type II DNA topoisomerases relax topological stress by transiently gating DNA passage in a controlled cut-and-reseal mechanism that affects both DNA strands.
Fernando M. Delgado-Chaves   +6 more
doaj   +1 more source

Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays [PDF]

open access: yesJournal of Biological Chemistry, 2019
Davood Norouzi   +2 more
exaly   +2 more sources

Fluorescently labeled circular DNA molecules for DNA topology and topoisomerases. [PDF]

open access: yesSci Rep, 2016
DNA topology plays essential roles in several fundamental biological processes, such as DNA replication, recombination, and transcription. Typically agarose gel electrophoresis is employed to study DNA topology.
Gu M   +5 more
europepmc   +2 more sources

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