Results 221 to 230 of about 230,805 (269)

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

An ATM-AMPK-Wip1 feedback loop governing DNA-damage signaling and tumor stress responses. [PDF]

Cell Death Dis
Gupta S, Panda PK.
europepmc   +1 more source

Rhenium Complexes as Antimicrobial Agents

Helvetica Chimica Acta, EarlyView.
Rhenium complexes are stepping into the fight against superbugs. Our new review explores how these metallic complexes could inspire the next generation of antimicrobial therapies. ABSTRACT The escalating crisis of antimicrobial resistance (AMR) necessitates the exploration of unconventional therapeutic scaffolds.
Fabio Zobi, Gozde Demirci, Marija Rasic
wiley   +1 more source

Functionally complementary bacterial inoculant coordinates arbuscular mycorrhizal fungi to improve Angelica sinensis root yield and quality

iMetaOmics, EarlyView.
Comprehensive understanding of how diverse PGPR strains enhance the rhizosphere microenvironment remains a considerable challenge. Here, we provide experimental evidence that a functionally synergistic composite microbial formulation can markedly enhance growth performance and improve the quality attributes in Angelica sinensis.
Zongyu Zhang, Yun Wang, Jiecai Zhao, Gaofeng Chen, Andéole Niyongabo Turatsinze, Liang Yue, Yuan Tian, Xiaofan Xie, Ailing Ye, Meilan Zhang, Lingling Wu, Zengxiang Guo, Yubao Zhang, Ruoyu Wang   +13 more
wiley   +1 more source

DNA topological regulation in RNA polymerase II transcription. [PDF]

Cell Mol Biol Lett
Bunch H.
europepmc   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

In-process analytics for IVT mRNA manufacturing: from process understanding to advanced process control. [PDF]

Front Bioeng Biotechnol
Kim N, Dong E, Tschudi K, Camperi J.
europepmc   +1 more source

Comprehensive spatial profiling reveals transitional microbiome dynamics and microbial heterogeneity in pediatric adenoid hypertrophy

iMetaOmics, EarlyView.
This study characterizes the upper respiratory microbiome in 276 children (101 Adenoid hypertrophy (AH) 119 Adenotonsillar hypertrophy (ATH), 11 Tonsil hypertrophy (TH), and 45 healthy controls by analyzing 1149 samples across five distinct niches: nasopharyngeal swabs (NS), adenoid swab (AS), and tonsil swabs (TS), plus adenoid tissues (AT) and tonsil
Kaining Chen, Xin Wan, Wenli Guo, Hongyan Yu, Yuantao Tong, Huiwen Ke, Junjie Fang, Xilian Luo, Di Che, Chao Hou, Xu Mei, Bingxue Hu, Yuehong Liu, Xiaoxiao Yu, Daoman Xiang, Wensi Chen, Yingjia Zeng, Yufen Xu, Jun Shen, Qiuxia Chen, Lei Pi, Lanyan Fu, Huazhong Zhou, Bingshao Liang, Meng Zhang, Yifan Dong, Yanqiu Chen, Wenhao Zhou, Xiaoqiong Gu   +28 more
wiley   +1 more source

Circular RNA therapeutics: a new class of long-acting RNA medicines for oncology, immunology, and rare diseases. [PDF]

Front Immunol
Ugwu OP, Okon MB, Ogenyi FC, Ugwu JN, Ugwu CN.   +4 more
europepmc   +1 more source

It's not me, it's you: Anti-phage nuclease specificity inside a bacterium. [PDF]

PLoS Pathog
Hong A, Bondy-Denomy J.
europepmc   +1 more source