Scattered organization of the histone multigene family and transposable elements in Synbranchus
Genetics and Molecular Biology, 2014 The fish species Synbranchus marmoratus is widely distributed throughout the Neotropical region and exhibits a significant karyotype differentiation. However, data concerning the organization and location of the repetitive DNA sequences in the genomes of
Ricardo Utsunomia +4 more
doaj +1 more source
Mangrove Forests: Natural Laboratories for Studying Epigenetic and Climate Changes
Frontiers in Plant Science, 2022 In the adaptation market, plants cash in the changes of their DNA (either genetic or epigenetic) to purchase fitness. Fitness is negatively affected by stressful conditions caused by climate change and well-designed studies are required to investigate ...
Matin Miryeganeh
doaj +1 more source
Conversion of DNA Sequences: From a Transposable Element to a Tandem Repeat or to a Gene [PDF]
Genes, 2019 Eukaryotic genomes are rich in repetitive DNA sequences grouped in two classes regarding their genomic organization: tandem repeats and dispersed repeats. In tandem repeats, copies of a short DNA sequence are positioned one after another within the genome, while in dispersed repeats, these copies are randomly distributed.
Ana Paço +2 more
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Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy
Advanced Science, EarlyView.This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan +11 more
wiley +1 more source
BMC GenomicsBackground The Peruvian ‘chanque’ or Chilean ‘loco’ Concholepas concholepas is an economically, ecologically, and culturally important muricid gastropod heavily exploited by artisanal fisheries in the temperate southeastern Pacific Ocean.
J. Antonio Baeza +4 more
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PLoS Genetics, 2023 Although homologous recombination between transposable elements can drive genomic evolution in yeast by facilitating chromosomal rearrangements, the details of the underlying mechanisms are not fully clarified.
Lei Qi +9 more
doaj
Phenotypic divergence of Homo sapiens is driven by the evolution of human-specific genomic regulatory networks via two mechanistically distinct pathways of creation of divergent regulatory DNA sequences [PDF]
arXiv, 2015 Thousands of candidate human-specific regulatory sequences (HSRS) have been identified, supporting the hypothesis that unique to human phenotypes result from human-specific alterations of genomic regulatory networks. Here, conservation patterns analysis of 18,364 candidate HSRS was carried out based on definition of the sequence conservation threshold ...
arxiv
Stochastic predator-prey dynamics of transposons in the human genome [PDF]
, 2016 Transposable elements, or transposons, are DNA sequences that can jump from site to site in the genome during the life cycle of a cell, usually encoding the very enzymes which perform their excision. However, some transposons are parasitic, relying on the enzymes produced by the regular transposons.
arxiv +1 more source
Single-molecule real-time sequencing combined with optical mapping yields completely finished fungal genome [PDF]
, 2015 Next-generation sequencing (NGS) technologies have increased the scalability, speed, and resolution of genomic sequencing and, thus, have revolutionized genomic studies.
Datema, Erwin +6 more
core +2 more sources
A MODEL FOR DNA SEQUENCE EVOLUTION WITHIN TRANSPOSABLE ELEMENT FAMILIES [PDF]
Genetics, 1986 ABSTRACT A quantitative model is proposed for the expected degree of relationship between copies of a family of transposable elements in a finite population of hosts. Special cases of the model (in which the process of homogenization of element copies either is or is not limited by transposition rate) are presented and illustrated, using
openaire +3 more sources