Results 191 to 200 of about 149,433 (366)

A Transcriptome‐Wide Mendelian Randomization Study in Isolated Human Immune Cells Highlights Risk Genes Involved in Viral Infections and Potential Drug Repurposing Opportunities for Schizophrenia

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey, Liam Gaziano, Preethi Eldi, Catherine Toben, Beben Benyamin, S. Hong Lee, Elina Hyppönen   +6 more
wiley   +1 more source

Supplementary Material for: Characterization and Genomic Organization of PERI, a Repetitive DNA in the Drosophila buzzatii Cluster Related to DINE-1 Transposable Elements and Highly Abundant in the Sex Chromosomes

, 2010
Kuhn G.C.S., J. S. Heslop‐Harrison
openalex   +2 more sources

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

Population Genetics and Molecular Evolution of DNA Sequences in Transposable Elements. I. A Simulation Framework

, 2013
Taizo Kijima, Hideki Innan
openalex   +1 more source

The structure of the regulatory region of the rat L1 (L1Rn, long interspersed repeated) DNA family of transposable elements [PDF]

, 1988
Anthony V. Furano, Susan M. Robb, Frank T. Robb   +2 more
openalex   +1 more source

Loss of Transposase-DNA Interaction May Underlie the Divergence of mariner Family Transposable Elements and the Ability of More than One mariner to Occupy the Same Genome [PDF]

, 2001
David J. Lampe, Kimberly K. O. Walden, Hugh M. Robertson   +2 more
openalex   +1 more source

DNA Methylation and Histone H1 Jointly Repress Transposable Elements and Aberrant Intragenic Transcripts.

Molecules and Cells, 2019
Jaemyung Choi, David B. Lyons, M. Y. Kim, Jonathan D. Moore, Daniel Zilberman   +4 more
semanticscholar   +1 more source

Honey Bee Breeding and Breed: Advancements, Challenges, and Prospects

Animal Research and One Health, EarlyView.
Our work clarifies concepts related to honey bee classification, reviews traditional and modern breeding techniques, explores advancements in molecular breeding, prospects gene‐editing tools, and advocates for integrated breeding strategies to ensure the long‐term sustainability and vitality of honey bee populations amid declining managed populations ...
Zheguang Lin, Lizhi Yang, Zhi Wang, Kang Wang, Qingsheng Niu, Ting Ji   +5 more
wiley   +1 more source

Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis [PDF]

, 2005
Robert K. Tran, Daniel Zilberman, Cecilia de Bustos, Renata Fava Ditt, Jorja G. Henikoff, Anders M. Lindroth, Jeffrey J. Delrow, Tom Boyle, Samson Kwong, Terri D. Bryson, Steven E. Jacobsen, Steven Henikoff   +11 more
openalex   +1 more source

Sex‐Based Differences in Prenatal and Perinatal Predictors of Autism Spectrum Disorder Using Machine Learning With National Health Data

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder influenced by genetic, epigenetic, and environmental factors. ASD is characterized by a higher prevalence in males compared to females, highlighting the potential role of sex‐specific risk factors in its development.
Ju Sun Heo, Seung‐Woo Yang, Sohee Lee, Kwang‐Sig Lee, Ki Hoon Ahn   +4 more
wiley   +1 more source