Results 271 to 280 of about 167,159 (369)

Variability of transposable elements in six genetic isolates from North-Eastern Italy and their relationship with alcohol consumption, tobacco use and BMI. [PDF]

BMC Genomics
Modenini G, Mercuri G, Abondio P, Nardone GG, Santin A, Tesolin P, Spedicati B, Pecori A, Pianigiani G, Concas MP, Girotto G, Gasparini P, Boattini A, Mezzavilla M.   +13 more
europepmc   +1 more source

From Genomic Fossils to Functional Elements: The Evolving Story of Pseudogenes

Advanced Genetics, EarlyView.
This review begins with an introduction, summarizing the research background in pseudogene studies. It then contains three aspects: identification of pseudogenes, detailing their classification and features in metazoan genomes; functional pseudogenes, introducing their reactivation and regulation mechanisms; and pseudogenes’ contribution to species ...
Mengyao Sun, Yanni Ma, Jia Yu
wiley   +1 more source

DNA methylation contributes to plant acclimation to naturally fluctuating light. [PDF]

New Phytol
Emmerson RA, Davey P, Kandjoze M, Bechtold U, Zabet NR, Lawson T.   +5 more
europepmc   +1 more source

The interplay between tissue‐resident microbiome and host proteins by integrated multi‐omics during progression of colorectal adenoma to carcinoma

iMeta, EarlyView.
This study integrated metagenomic and proteomic profiling of 185 colorectal tissue samples—spanning adenoma (A), tumor (T), and para‐tumor (P)—to characterize multi‐kingdom microbiome and host protein dynamics in colorectal cancer (CRC). In total, 4057 bacterial, 61 fungal, 108 archaeal, and 374 viral species were identified, revealing CRC‐specific ...
Di Wu, An‐Jun Wang, De‐Chao Bu, Yan‐Yan Sun, Chen‐Hao Li, Yue‐Mei Hong, Shan Zhang, Shi‐Yang Chen, Jin‐An Zhou, Tian‐Yi Zhang, Min‐Hao Yu, Yong‐Jing Ma, Xiu‐Li Wang, Jia Xu, Wei He, Christopher Heeschen, Jian‐Feng Chen, Wen‐Jun Mao, Hui Ding, Wen‐Juan Wu, Yi Zhao, Hui Wang, Ning‐Ning Liu   +22 more
wiley   +1 more source

Satellite DNAs rising from the transposon graveyards. [PDF]

DNA Res
Šatović-Vukšić E, Majcen P, Plohl M.
europepmc   +1 more source

Genome‐wide CRISPR screen reveals an uncharacterized spliceosome regulator as new candidate immunotherapy target

iMeta, EarlyView.
This study identifies the uncharacterized gene C9ORF50 as a novel regulator of immune evasion. Functioning as an intrinsically disordered protein, C9ORF50 drives liquid‐liquid phase separation to facilitate spliceosome assembly and maintain RNA splicing fidelity.
Tong Shao, Chuanyang Liu, Jingyu Kuang, Sisi Xie, Ying Qu, Yingying Li, Lulu Zhang, Fangzhou Liu, Yanhua Qi, Tao Hou, Ming Li, Sujuan Zhang, Yu Liu, Zhixiang Yuan, Jiali Liu, Yanming Hu, Jingyang Wang, Chenghu Song, Shaowei Zhang, Lingyun Zhu, Jianzhong Shao, Aifu Lin, Wenjun Mao, Guangchuan Wang, Lvyun Zhu   +24 more
wiley   +1 more source

Improved genome assembly of Onygena corvina, a keratin-degrading fungus. [PDF]

BMC Res Notes
Pavale S, Eijsink VGH, La Rosa SL.
europepmc   +1 more source

Hurricane Impacts on the Population Genetics of an Endangered Ecosystem Engineer 飓风对一种濒危生态系统工程师的种群遗传学影响

Integrative Conservation, EarlyView.
Key Largo woodrats are a small and endangered island species, whose individuals tend to occur in family groups. Isolation from mainland populations, predation, and habitat fragmentation have caused genetic drift, leading to low overall diversity. Here, we found that a major category 4 hurricane promoted genetic diversity in the Key Largo woodrat ...
Taylor Ackley, Martha Burford Reiskind, Emily C. Moore, Jeremy D. Dixon, Michael V. Cove, Elizabeth M. Kierepka   +5 more
wiley   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

The role of toxin/antidote genes in the maintenance and evolution of accessory chromosomes in Fusarium. [PDF]

Genetics
Sandell L, Forsythe A, Mirandola A, Jorayev S, Urquhart AS, Granger Farbos A, Saupe SJ, Vogan AA.   +7 more
europepmc   +1 more source