Results 11 to 20 of about 191,032 (247)

DNA Vaccine Construct Formation using Mycobacterium-Specific Gene Inh-A

open access: yesJournal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022
BACKGROUND: Tuberculosis (TB) remains a highly contagious disease and a leading cause of death worldwide. It is caused by Mycobacterium tuberculosis and Mycobacterium bovis. TB infection is still uncontrolled because of the unavailability of an effective
Summayya Anwar   +4 more
doaj   +1 more source

The Immunogenicity and Protective Efficacy of DNA Vaccine Coding For NA1 Gene of Highly Pathogenic Avian Influenza H5N1 Subtype

open access: yesJournal of Applied Veterinary Sciences, 2020
Control of avian influenza infection depends mainly on biosafety measures and vaccination, DNA vaccination is a novel method to generate antigen-specific antibody and cell-mediated immunity. In the current study, a DNA vaccine for full-length N1 gene was
Soliman YA   +3 more
doaj   +1 more source

DNA Vaccines.

open access: yesCurrent Molecular Medicine, 2001
Within the last decade bacterial plasmids encoding foreign antigens have revolutionized vaccine design. Although no DNA vaccine has yet been approved for routine human or veterinary use, the potential of this vaccine modality has been demonstrated in experimental animal models.
Reyes-Sandoval, A, Ertl, H
openaire   +4 more sources

Vaccines to prevent Ebola virus disease: current challenges and perspectives

open access: yesВопросы вирусологии, 2023
Relevance. Ebola virus disease (EVD) is an acute infectious disease with an extremely high case fatality rate reaching up to 90%. EVD has become widely known since 20142016, when outbreak in West Africa occurred and led to epidemic, which caused travel ...
Anna V. Kovyrshina   +6 more
doaj   +1 more source

The dna vaccine combining the adjuvant porcine il-12 with the spike gene of transmissible gastroenteritis virus enhances the immune response in swine [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2018
Transmissible gastroenteritis (TGE), cause by transmissible gastroenteritis virus (TGEV), is an acute digestive and highly infectious disease in piglets. In this study, porcine interleukin-12 immunological adjuvant combined with a DNA vaccine bearing the
Xunliang LI   +5 more
doaj   +1 more source

Modified DNA vaccine confers improved humoral immune response and effective virus protection against SARS-CoV-2 delta variant

open access: yesScientific Reports, 2022
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global pandemic. New technologies have been utilized to develop several types of vaccines to prevent the spread of SARS-CoV-2 ...
Hiroki Hayashi   +20 more
doaj   +1 more source

DNA Based Vaccines against Mycobacterium Tuberculosis: Recent Progress in Vaccine Development and Delivery System [PDF]

open access: yesIranian Journal of Immunology, 2020
Tuberculosis (TB) is believed to be one of the leading causes of death in the world; nevertheless, Bacillus Calmette-Guérin (BCG) is the solitary vaccine utilized to prevent TB.
Ahmad Mobed
doaj   +1 more source

Immunotherapeutic effects of Mycobacterium tuberculosis rv3407 DNA vaccine in mice

open access: yesAutoimmunity, 2018
Tuberculosis (TB) is a major global public health problem. Latent TB infection (LTBI) is a major source of active TB. New vaccines to treat LTBI are urgently demanded.
Yan Liang   +11 more
doaj   +1 more source

Dissolving microneedles for DNA vaccination: Improving functionality via polymer characterization and RALA complexation

open access: yesHuman Vaccines & Immunotherapeutics, 2017
DNA vaccination holds the potential to treat or prevent nearly any immunogenic disease, including cancer. To date, these vaccines have demonstrated limited immunogenicity in vivo due to the absence of a suitable delivery system which can protect DNA from
Grace Cole   +7 more
doaj   +1 more source

Advancements in the development of nucleic acid vaccines for syphilis prevention and control

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Syphilis, a chronic systemic sexually transmitted disease, is caused by the bacterium Treponema pallidum (T. pallidum). Currently, syphilis remains a widespread infectious disease with significant disease burden in many countries.
Sijia Li   +4 more
doaj   +1 more source

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