Results 51 to 60 of about 1,964,734 (294)

In Vivo Electroporation Enhances the Immunogenicity of an HIV-1 DNA Vaccine Candidate in Healthy Volunteers [PDF]

, 2011
10.08.12 KB OA publisher, published version ok to add to Spiral.
Schmidt, C, Lorna Clark, Arlene Hurley, Kopycinski Jakub T., David D. Ho, Caskey, M, Clark, L, Hannaman, D, Gilmour Jill, Schlesinger, SJ, Cheeseman Hannah, Hurley Arlene, Smith Carol, Hurley, A, Ho, DD, Cheeseman, H, Ho David D., Caskey Marina, Fast Patricia, Dally, L, Marina Caskey, Gill Dilbinder K., Roselle Vittorino, Vasan, S, Sarah J Schlesinger, Andersen, J, Harriet H Park, Patricia Fast, Bernard Robert, Clark Lorna, Vittorino, R, Gardiner David F., Josephine H Cox, Dilbinder K. Gill, Dally Len, Robert Bernard, Vasan Sandhya, Josephine H. Cox, Jill Gilmour, Claudia Schmidt, Andersen Johanne, Johanne Andersen, Jakub T Kopycinski, Park Harriet H., Cox, JH, Smith, C, David F Gardiner, Gilmour, J, Harriet H. Park, Tony Tarragona-Fiol, Huang Yaoxing, Sarah J. Schlesinger, Len Dally, Gill, DK, Dilbinder K Gill, Cox Josephine H., Bernard, R, Boente-Carrera, M, Boente-Carrera Mar, Hannah Cheeseman, Sandhya Vasan, Carol Smith, Schlesinger Sarah J., Fast, P, Park, HH, Drew Hannaman, Schmidt Claudia, Tarragona-Fiol, T, Kopycinski, JT, Jakub T. Kopycinski, Huang, Y, Mar Boente-Carrera, Gardiner, DF, Yaoxing Huang, Hannaman Drew, Tarragona-Fiol Tony, Dugin, DP, Daniel P. Dugin, Daniel P Dugin, Vittorino Roselle, Dugin Daniel P., David D Ho, David F. Gardiner   +82 more
core   +2 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Experimental DNA-Launched Live-Attenuated Vaccines Against Yellow Fever

Эпидемиология и вакцинопрофилактика, 2019
Background DNA-launched vaccine is “manufactured” in vaccinated individuals and does not require traditional vaccine manufacturing facility and technology. Goals.
P. Pushko, А. А. Ishmukhametov, P. P. Bredenbeek, I. S. Lukashevich   +3 more
doaj   +1 more source

Evidence of blood stage efficacy with a virosomal malaria vaccine in a Phase IIa clinical trial [PDF]

, 2008
Background Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine.
Zurbriggen, R, Gerd Pluschke, Sarah C. Gilbert, Hill, Adrian, Hutchings, Claire, Gilbert Sarah C., Sinden, Robert, Gilbert, Sarah, Pluschke, G, Gilbert, Sarah C., Zurbriggen Rinaldo, Vogel, Denise, Jack L. Williams, Correa, S, Andrews Laura, Okitsu, SL, Westerfeld Nicole, Andrews, Laura, Vogel, D, David W. Porter, Thompson, Fiona, Okitsu, Shinji, Ian Poulton, Todryk, S, Shinji L. Okitsu, Denise Vogel, Dunachie Susanna, Thompson Fiona M., Berthoud, Tamara, Andrews, L, Sinden, R, Porter David W., Pluschke, Gerd, Sarah C Gilbert, Sinden Robert, Poulton Ian, Fiona M Thompson, Berthoud, T, Zurbriggen, Rinaldo, Rinaldo Zurbriggen, Susanna Dunachie, Westerfeld, Nicole, Tamara Berthoud, Todryk, Stephen, Okitsu Shinji L., Hill Adrian V. S., Correa Simon, Berthoud Tamara, Dunachie, S, Westerfeld, N, David W Porter, Nicole Westerfeld, Todryk Stephen, Porter, David, Correa, Simon, Thompson, FM, Pluschke Gerd, Hutchings, C, Poulton, Ian, Hutchings Claire, Williams, JL, Vogel Denise, Shinji L Okitsu, Fiona M. Thompson, Poulton, I, Jack L Williams, Simon Correa, Laura Andrews, Dunachie, Susanna, Adrian V S Hill, Robert Sinden, Porter, DW, Stephen Todryk, Williams, Jack, Claire Hutchings, Williams Jack L.   +75 more
core   +1 more source

Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus

, 2021
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide.
조상래
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

DNA vaccine: the miniature miracle

Veterinary World, 2013
DNA, the essential part of the life is making way in to new vaccine technology. Plasmid vectors from the bacteria have revolutionized the world of vaccine design by its new technology – DNA vaccines.
Karthik Kaliaperumal, Karthik Kumaragurubaran   +1 more
doaj   +1 more source

Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge

Human Vaccines & Immunotherapeutics, 2020
Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–Barré ...
Hyeree Choi, Sagar B. Kudchodkar, Emma L. Reuschel, Kanika Asija, Piyush Borole, Sangya Agarwal, Lucas Van Gorder, Charles C. Reed, Gayathri Gulendran, Stephanie Ramos, Kate E. Broderick, J Joseph Kim, Kenneth E. Ugen, Gary Kobinger, Don L. Siegel, David B. Weiner, Kar Muthumani   +16 more
doaj   +1 more source

Omicron Booster in Ancestral Strain Vaccinated Mice Augments Protective Immunities Against Both Delta and Omicron Variants

Frontiers in Immunology, 2022
A booster vaccination is called for constraining the evolving epidemic of SARS-CoV-2. However, the necessity of a new COVID-19 vaccine is currently unclear.
Liqiu Jia, Yang Zhou, Shaoshuai Li, Shaoshuai Li, Shaoshuai Li, Yifan Zhang, Yifan Zhang, Yifan Zhang, Dongmei Yan, Wanhai Wang, Wenhong Zhang, Wenhong Zhang, Wenhong Zhang, Yanmin Wan, Yanmin Wan, Chao Qiu, Chao Qiu   +16 more
doaj   +1 more source

Vaccination with DNA encoding cysteine proteinase confers protective immune response to rats infected with Clonorchis sinensis

, 2006
Cysteine proteinases of C. sinensis are important virulence factors that induce pathological changes associated with larval migration and localized biliary epithelial destruction.
용태순
core   +1 more source