Results 51 to 60 of about 210,905 (300)

Experimental DNA-Launched Live-Attenuated Vaccines Against Yellow Fever

Эпидемиология и вакцинопрофилактика, 2019
Background DNA-launched vaccine is “manufactured” in vaccinated individuals and does not require traditional vaccine manufacturing facility and technology. Goals.
P. Pushko, А. А. Ishmukhametov, P. P. Bredenbeek, I. S. Lukashevich   +3 more
doaj   +1 more source

Vaccination with DNA encoding cysteine proteinase confers protective immune response to rats infected with Clonorchis sinensis

, 2006
Cysteine proteinases of C. sinensis are important virulence factors that induce pathological changes associated with larval migration and localized biliary epithelial destruction.
용태순
core   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

DNA vaccine: the miniature miracle

Veterinary World, 2013
DNA, the essential part of the life is making way in to new vaccine technology. Plasmid vectors from the bacteria have revolutionized the world of vaccine design by its new technology – DNA vaccines.
Karthik Kaliaperumal, Karthik Kumaragurubaran   +1 more
doaj   +1 more source

Omicron Booster in Ancestral Strain Vaccinated Mice Augments Protective Immunities Against Both Delta and Omicron Variants

Frontiers in Immunology, 2022
A booster vaccination is called for constraining the evolving epidemic of SARS-CoV-2. However, the necessity of a new COVID-19 vaccine is currently unclear.
Liqiu Jia, Yang Zhou, Shaoshuai Li, Shaoshuai Li, Shaoshuai Li, Yifan Zhang, Yifan Zhang, Yifan Zhang, Dongmei Yan, Wanhai Wang, Wenhong Zhang, Wenhong Zhang, Wenhong Zhang, Yanmin Wan, Yanmin Wan, Chao Qiu, Chao Qiu   +16 more
doaj   +1 more source

DNA vaccines for biodefense [PDF]

Expert Review of Vaccines, 2009
An ideal biodefense vaccine platform would allow for the quick formulation of novel vaccines in response to emerging or engineered pathogens. The resultant vaccine should elicit protective immune responses in one to three doses and be unaffected by pre-existing immunity to vaccine components.
Dupuy, Lesley C., Schmaljohn, Connie S.
openaire   +2 more sources

A review of the tolerability of the candidate TB vaccine, MVA85A compared with BCG and Yellow Fever vaccines, and correlation between MVA85A vaccine reactogenicity and cellular immunogenicity [PDF]

, 2012
© 2012 Elsevier Ltd. All rights reservedBackground: The development of a new, more effective vaccine against tuberculosis (TB) for use in healthy and HIV-infected adults, children and infants, remains a global health priority.
Minassian, Angela M, Porter, David W, Pathan, Ansar A, Rowland, Rosalind, Sander, C, Satti, Iman, Angela M Minassian, Nicola Williams, Lawrie, AM, Sander, Clare, Alison M Lawrie, Rowland, R, Poulton, ID, Rosalind Rowland, Brittain, N, Williams, Nicola, Pathan, AA, David W Porter, Minassian, AM, Helen McShane, Iman Satti, Ansar A Pathan, Ian D Poulton, Lawrie, Alison M, Nathaniel Brittain, Williams, N, Brittain, Nathaniel, Poulton, Ian D, Clare Sander, Porter, DW, Satti, I, McShane, H, McShane, Helen   +32 more
core   +1 more source

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

Advanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park, Yidam Song, Hyun‐Woo Choi, Jaeuk Sung, Harin Jin, WonSeok Gwak, Kirim Yoo, Soohwang Lee, Jongeon Park, Jeongmin Kim, Hye‐Jun Jo, Jahyun Koo, Youngdo Jeong, Kwan Hyi Lee, Seung‐Jung Kee, Hojun Kim   +15 more
wiley   +1 more source

Immune-enhancing effects of Taishan Pinus massoniana pollen polysaccharides on DNA vaccine expressing Bordetella avium ompA

Frontiers in Microbiology, 2016
Bordetella avium is the causative agent of bordetellosis, which remains to be the cause of severe losses in the turkey industry. Given the lack of vaccines that can provide good protection, developing a novel vaccine against B. avium infection is crucial.
Fujie eZhu, Xiao eLiu, Zhenhong eSun, Cuilian eYu, Liping eLiu, Shifa eYang, Bing eLi, Kai eWei, Ruiliang eZhu   +8 more
doaj   +1 more source

Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge

Human Vaccines & Immunotherapeutics, 2020
Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–Barré ...
Hyeree Choi, Sagar B. Kudchodkar, Emma L. Reuschel, Kanika Asija, Piyush Borole, Sangya Agarwal, Lucas Van Gorder, Charles C. Reed, Gayathri Gulendran, Stephanie Ramos, Kate E. Broderick, J Joseph Kim, Kenneth E. Ugen, Gary Kobinger, Don L. Siegel, David B. Weiner, Kar Muthumani   +16 more
doaj   +1 more source