DNA Vaccines Approach: From Concepts to Applications
, 2014 DNA vaccines are the third generation vaccines based on purified plasmid preparations containing transgenes that encode antigenic/therapeutic proteins or peptides capable of triggering an immune response against a wide range of diseases.
V. B. Pereira +12 more
semanticscholar +1 more source
Tipping the Proteome with Gene-Based Vaccines: Weighing in on the Role of Nanomaterials
Journal of Nanotechnology, 2012 Since the first generation of DNA vaccines was introduced in 1988, remarkable improvements have been made to improve their efficacy and immunogenicity.
Kristin J. Flores +6 more
doaj +1 more source
Novel particulate vaccine candidates recombinantly produced by pathogenic and nonpathogenic bacterial hosts : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Microbiology at Massey University, Manawatu, New Zealand. [PDF]
, 2017 Polyhydroxyalkanoates (PHAs) are biopolyesters synthesized as small spherical cytoplasmic inclusion bodies by a range of bacteria. Recently, PHA beads have been investigated for use as a vaccine delivery platform by using engineered heterologous ...
Lee, Jason Wong
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DNA vaccines against COVID-19: Perspectives and challenges
Life Science, 2020 M. Silveira +2 more
semanticscholar +1 more source
DNA vaccines: prime time is now
Current Opinion in Immunology, 2020 E. Gary, D. Weiner
semanticscholar +1 more source
Systems Biology and the Development of Vaccines and Drugs for Malaria Treatments [PDF]
, 2006 The sequencing race has ended and the functional race has already begun. Microarray technology enables simultaneous gene expression analysis of thousands of genes, enabling a snapshot of an organisms’ transcriptome at an unprecedented resolution.
Adebiyi, E. F.
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Advances in nucleic acid-based cancer vaccines
Journal of Biomedical ScienceNucleic acid vaccines have emerged as crucial advancements in vaccine technology, particularly highlighted by the global response to the COVID-19 pandemic.
Hung-Chun Liao, Shih-Jen Liu
doaj +1 more source
Identification and characterisation of toxin-antitoxin systems (TA) in Burkholderia pseudomallei [PDF]
, 2013 The aim of this study was to identify and characterise type II toxin-antitoxin (TA) systems in Burkholderia pseudomallei, the causative agent of the human disease melioidosis. 8 putative TA systems were identified within the genome of B. pseudomallei
Butt, Aaron Trevor
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Securing poultry production from the ever-present Eimeria challenge [PDF]
, 2013 Blake, D P, Tomley, F M
core +2 more sources
Enhanced antigen presentation and immunostimulation of dendritic cells using acid-degradable cationic nanoparticles. [PDF]
, 2005 Acid-degradable cationic nanoparticles encapsulating a model antigen (i.e., ovalbumin) were prepared by inverse microemulsion polymerization with acid-cleavable acetal cross-linkers.
Fréchet, Jean MJ +3 more
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