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Production and purification of plasmid DNA vaccines: is there scope for further innovation?
Expert Review of Vaccines, 2014The demand for plasmid DNA (pDNA) has vastly increased over the past decade in response to significant advances that have been made in its application for gene therapy and vaccine development.
A. Xenopoulos, Priyabrata Pattnaik
semanticscholar +1 more source
2006
The purpose of this chapter is to present basic strategies for the construction of DNA vaccines. This chapter discusses considerations relevant to the selection of a target gene, construction of a DNA expression vector for use as a vaccine, and molecular modifications of the vector to improve protein expression and to augment immunogenicity.
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The purpose of this chapter is to present basic strategies for the construction of DNA vaccines. This chapter discusses considerations relevant to the selection of a target gene, construction of a DNA expression vector for use as a vaccine, and molecular modifications of the vector to improve protein expression and to augment immunogenicity.
openaire +2 more sources
Plasmid DNA vaccines: where are we now?
Drugs of Today, 2018F. Ghaffarifar
semanticscholar +1 more source
Engineering nanoparticle-coated bacteria as oral DNA vaccines for cancer immunotherapy.
Nano letters (Print), 2015Q. Hu +8 more
semanticscholar +1 more source
DNA vaccination/genetic vaccination.
Current topics in microbiology and immunology, 1998H, Koprowski, D B, Weiner
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Annales pharmaceutiques francaises, 2003
DNA vaccination is a new vaccine approach used to induce an immune response to an antigen protein expressed in vivo. It is based on the introduction, via intramuscular injections, particle bombardment, or nasal spray, of a purified DNA plasmid encoding for the polypeptide sequence.
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DNA vaccination is a new vaccine approach used to induce an immune response to an antigen protein expressed in vivo. It is based on the introduction, via intramuscular injections, particle bombardment, or nasal spray, of a purified DNA plasmid encoding for the polypeptide sequence.
openaire +1 more source
DNA vaccines: immunology, application, and optimization*.
Annual Review of Immunology, 2000S. Gurunathan, D. Klinman, R. Seder
semanticscholar +1 more source
Comparative genomics of BCG vaccines by whole-genome DNA microarray.
Science, 1999M. Behr +6 more
semanticscholar +1 more source
Using Plasmids as DNA Vaccines for Infectious Diseases
Microbiology spectrum, 2014J. Tregoning, E. Kinnear
semanticscholar +1 more source
DNA vaccines against tuberculosis
Expert Opinion on Biological Therapy, 2014N. Bruffaerts, K. Huygen, M. Romano
semanticscholar +1 more source