Results 171 to 180 of about 171,936 (284)

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants. [PDF]

PLoS One, 2023
Kim SE, Park SH, Park WJ, Kim G, Kim SY, Won H, Hwang YH, Lim H, Kim HG, Kim YJ, Kim D, Lee JA.   +11 more
europepmc   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Phase 2 trial of pTVG-HP ± pTVG-AR DNA vaccines and pembrolizumab in patients with metastatic, castration-resistant prostate cancer (mCRPC). [PDF]

J Immunother Cancer
Kyriakopoulos CE, Pachynski RK, Eickhoff JC, Tonelli TP, Jeon D, McNeel DG.   +5 more
europepmc   +1 more source

Multiantigen pan-sarbecovirus DNA vaccines generate protective T cell immune responses. [PDF]

JCI Insight, 2023
van Bergen J, Camps MG, Pardieck IN, Veerkamp D, Leung WY, Leijs AA, Myeni SK, Kikkert M, Arens R, Zondag GC, Ossendorp F.   +10 more
europepmc   +1 more source

DNA fusion gene vaccines

, 2010
Udgivelsesdato: 2010-FebDNA vaccines are versatile and safe, but limited immunogenicity has prevented their use in the clinical setting. Experimentally, immunogenicity may be enhanced by the use of new delivery technologies, by coadministration of ...
Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Holst, Peter Johannes, Bassi, Maria Rosaria   +3 more
core  

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

DNA Vaccines in the Post-mRNA Era: Engineering, Applications, and Emerging Innovations. [PDF]

Int J Mol Sci
Neeli P, Chai D, Roy D, Prajapati S, Bonam SR.   +4 more
europepmc   +1 more source

Comparison of DNA vaccines with AddaS03 as an adjuvant and an mRNA vaccine against SARS-CoV-2. [PDF]

iScience, 2023
Neeli P, Chai D, Wang X, Sobhani N, Udeani G, Li Y.   +5 more
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Chitosan nanoparticles as next-generation carriers for veterinary DNA vaccines: Mechanisms, immune responses, and translational prospects. [PDF]

Vet World
González-Lozano M, Cano-Buendía JA.
europepmc   +1 more source