Results 61 to 70 of about 3,025,811 (189)
A Novel Formulation Strategy to Deliver Combined DNA and VLP Based HPV Vaccine
Journal of Pharmacy & Pharmaceutical Sciences, 2019 Human papillomaviruses (HPV) are small, double-stranded DNA viruses that cause cervical cancer, the second most lethal cancer among women in the world. Currently, two vaccines are on the market for preventing HPV-caused cervical cancers and warts.
Mohammad Nasir Uddin +4 more
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Vaccines, 2023 The combination of mosaic Gag and CAP256 envelope in an HIV vaccine regimen comprising DNA prime and modified vaccinia Ankara (MVA) boost followed by protein boost has previously been shown to generate robust autologous Tier 2 neutralizing antibodies ...
Rosamund Chapman +5 more
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Mucosal vaccines — fortifying the frontiers
Nature reviews. Immunology, 2021 Mucosal vaccines offer the potential to trigger robust protective immune responses at the predominant sites of pathogen infection. In principle, the induction of adaptive immunity at mucosal sites, involving secretory antibody responses and tissue ...
E. Lavelle, Ross W. Ward
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DNA vaccine: Methods and mechanisms
Advances in Human Biology, 2018 Infectious diseases are the biggest cause of mortality and morbidity in humans, especially in poor and developing countries. For many years, no new vaccine has been developed, which indicates the limitations of the development of common vaccines ...
Saber Soltani +5 more
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Журнал микробиологии, эпидемиологии и иммунобиологииIntroduction. During the COVID-19 pandemic, the development of preventive vaccines, including those based on new platforms, became extremely relevant.
Mariya B. Borgoyakova +16 more
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, 2005 The DNA vaccine has proven to be one of the most promising applications in the field of gene therapy. Due to its unique ability to readily induce humoral as well as cellular immune responses, it attracted great interest when the concept was first confirmed in the early 1990s.
openaire +2 more sources
Pharmaceutics, 2014 Intranasal delivery of DNA vaccines has become a popular research area recently. It offers some distinguished advantages over parenteral and other routes of vaccine administration.
Yingying Xu +2 more
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Removing N-terminal sequences in pre-S1 domain enhanced antibody and B-cell responses by an HBV large surface antigen DNA vaccine. [PDF]
PLoS ONE, 2012 Although the use of recombinant hepatitis B virus surface (HBsAg) protein vaccine has successfully reduced global hepatitis B infection, there are still a number of vaccine recipients who do not develop detectable antibody responses.
Guohong Ge +5 more
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Prophylactic and therapeutic DNA vaccines against Chagas disease
Parasites & Vectors, 2015 Chagas disease is a zoonosis caused by Trypanosoma cruzi in which the most affected organ is the heart. Conventional chemotherapy has a very low effectiveness; despite recent efforts, there is currently no better or more effective treatment available ...
M. Arce-Fonseca +4 more
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Cytolytic Perforin as an Adjuvant to Enhance the Immunogenicity of DNA Vaccines
Vaccines, 2019 DNA vaccines present one of the most cost-effective platforms to develop global vaccines, which have been tested for nearly three decades in preclinical and clinical settings with some success in the clinic.
Ashish C. Shrestha +5 more
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